I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| enterocyte | 5 studies | 39% ± 11% | |
| epithelial cell | 5 studies | 22% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| enterocyte | 5 studies | 39% ± 11% | |
| epithelial cell | 5 studies | 22% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| intestine | 3 studies | 21% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 82% | 990.57 | 791 / 966 | 89% | 110.35 | 470 / 527 |
| stomach | 63% | 12.36 | 225 / 359 | 80% | 80.82 | 228 / 286 |
| pancreas | 66% | 6.32 | 217 / 328 | 75% | 27.85 | 134 / 178 |
| kidney | 99% | 97.06 | 88 / 89 | 36% | 13.97 | 323 / 901 |
| ureter | 0% | 0 | 0 / 0 | 100% | 24.61 | 1 / 1 |
| thymus | 95% | 24.52 | 622 / 653 | 3% | 0.23 | 17 / 605 |
| prostate | 88% | 28.02 | 215 / 245 | 1% | 0.07 | 4 / 502 |
| lung | 47% | 4.06 | 270 / 578 | 42% | 28.61 | 483 / 1155 |
| bladder | 43% | 3.00 | 9 / 21 | 43% | 44.21 | 215 / 504 |
| esophagus | 31% | 3.26 | 451 / 1445 | 39% | 14.24 | 72 / 183 |
| skin | 65% | 9.56 | 1173 / 1809 | 0% | 0 | 0 / 472 |
| breast | 57% | 13.32 | 261 / 459 | 6% | 0.76 | 65 / 1118 |
| uterus | 20% | 1.71 | 34 / 170 | 11% | 5.45 | 52 / 459 |
| liver | 15% | 0.83 | 35 / 226 | 11% | 3.07 | 45 / 406 |
| spleen | 24% | 1.57 | 59 / 241 | 0% | 0 | 0 / 0 |
| brain | 23% | 2.04 | 619 / 2642 | 0% | 0 | 0 / 705 |
| ovary | 8% | 0.42 | 15 / 180 | 12% | 1.79 | 52 / 430 |
| adipose | 8% | 0.55 | 101 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.56 | 2 / 29 |
| adrenal gland | 6% | 0.34 | 15 / 258 | 1% | 0.18 | 2 / 230 |
| peripheral blood | 4% | 0.19 | 34 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 3% | 0.17 | 38 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 2% | 0.10 | 19 / 803 | 0% | 0 | 0 / 0 |
| heart | 1% | 0.07 | 12 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| GO_1905184 | Biological process | positive regulation of protein serine/threonine phosphatase activity |
| GO_0042325 | Biological process | regulation of phosphorylation |
| GO_1905183 | Biological process | negative regulation of protein serine/threonine phosphatase activity |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0004865 | Molecular function | protein serine/threonine phosphatase inhibitor activity |
| Gene name | PPP1R14D |
| Protein name | Protein phosphatase 1 regulatory subunit 14 Protein phosphatase 1 regulatory subunit 14D (Gastrointestinal and brain-specific PP1-inhibitory protein 1) (GBPI-1) |
| Synonyms | GBPI |
| Description | FUNCTION: Inhibitor of PPP1CA. Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. . FUNCTION: Inhibitor of PPP1CA. . FUNCTION: Inhibitor of PPP1CA. . |
| Accessions | ENST00000299174.10 ENST00000427255.2 Q4V755 Q9NXH3 E9PAT1 |
