I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 14 studies | 33% ± 15% | |
| glutamatergic neuron | 3 studies | 25% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 14 studies | 33% ± 15% | |
| glutamatergic neuron | 3 studies | 25% ± 3% |
Insufficient scRNA-seq data for expression of PPOX at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 1430.11 | 180 / 180 | 100% | 14.71 | 430 / 430 |
| skin | 100% | 984.00 | 1809 / 1809 | 100% | 15.56 | 472 / 472 |
| brain | 100% | 933.04 | 2638 / 2642 | 100% | 16.58 | 705 / 705 |
| thymus | 100% | 1464.87 | 653 / 653 | 100% | 13.35 | 604 / 605 |
| breast | 100% | 1161.97 | 459 / 459 | 100% | 17.05 | 1116 / 1118 |
| uterus | 100% | 1476.64 | 170 / 170 | 100% | 14.75 | 458 / 459 |
| prostate | 100% | 1441.21 | 245 / 245 | 99% | 13.49 | 499 / 502 |
| liver | 99% | 475.71 | 224 / 226 | 100% | 12.23 | 406 / 406 |
| bladder | 100% | 1073.24 | 21 / 21 | 99% | 15.27 | 499 / 504 |
| pancreas | 99% | 567.85 | 326 / 328 | 99% | 10.46 | 177 / 178 |
| adrenal gland | 100% | 1467.91 | 258 / 258 | 99% | 12.64 | 227 / 230 |
| intestine | 100% | 1049.20 | 966 / 966 | 97% | 8.07 | 513 / 527 |
| kidney | 100% | 1208.97 | 89 / 89 | 97% | 11.66 | 877 / 901 |
| lung | 99% | 987.87 | 575 / 578 | 97% | 10.79 | 1126 / 1155 |
| stomach | 100% | 787.10 | 359 / 359 | 96% | 7.17 | 275 / 286 |
| esophagus | 100% | 877.02 | 1444 / 1445 | 95% | 6.50 | 174 / 183 |
| adipose | 100% | 919.95 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 15.11 | 29 / 29 |
| spleen | 100% | 1545.24 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 11.46 | 1 / 1 |
| blood vessel | 100% | 839.97 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 10.13 | 79 / 80 |
| heart | 99% | 537.54 | 850 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 698.87 | 913 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 8.58 | 43 / 45 |
| muscle | 92% | 324.48 | 741 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006782 | Biological process | protoporphyrinogen IX biosynthetic process |
| GO_0006783 | Biological process | heme biosynthetic process |
| GO_0006784 | Biological process | heme A biosynthetic process |
| GO_0006779 | Biological process | porphyrin-containing compound biosynthetic process |
| GO_0048034 | Biological process | heme O biosynthetic process |
| GO_0006785 | Biological process | heme B biosynthetic process |
| GO_0031966 | Cellular component | mitochondrial membrane |
| GO_0005758 | Cellular component | mitochondrial intermembrane space |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0050660 | Molecular function | flavin adenine dinucleotide binding |
| GO_0004729 | Molecular function | oxygen-dependent protoporphyrinogen oxidase activity |
| Gene name | PPOX |
| Protein name | Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4) Protoporphyrinogen oxidase (EC 1.3.3.4) Mutant protoporphyrinogen oxidase Protoporphyrinogen oxidase |
| Synonyms | hCG_1766487 |
| Description | FUNCTION: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. . FUNCTION: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. . FUNCTION: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. . FUNCTION: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. . |
| Accessions | F5H825 A0A494C146 F5GZT7 F5H1I5 P50336 A0A494C0M9 Q96SE3 ENST00000652182.1 ENST00000652103.1 D3DVG2 Q96TC9 A0A1W2PQM0 A0A494C0L4 ENST00000367999.9 ENST00000537829.1 ENST00000537523.5 ENST00000352210.9 A0A494C134 ENST00000535223.5 A0A494C1M8 Q96RP0 A0A494C0D4 ENST00000651150.1 ENST00000495483.5 ENST00000650741.1 A0A494C0C8 ENST00000544598.5 A0A1W2PNH4 A0A1W2PPA5 ENST00000497522.5 ENST00000539753.5 ENST00000462866.5 A0A1W2PRF9 H0YFP3 ENST00000470607.5 ENST00000652100.1 ENST00000652729.1 ENST00000652473.1 ENST00000652297.1 H0YFE1 |
