PLAAT5 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PLAAT5 at tissue level.

III. Associated gene sets

GO_0070292Biological processN-acylphosphatidylethanolamine metabolic process
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0004623Molecular functionphospholipase A2 activity
GO_0016410Molecular functionN-acyltransferase activity
GO_0008970Molecular functionphospholipase A1 activity
GO_0052739Molecular functionphosphatidylserine 1-acylhydrolase activity
GO_0052740Molecular function1-acyl-2-lysophosphatidylserine acylhydrolase activity

IV. Literature review

[source]
Gene namePLAAT5
Protein namePhospholipase A and acyltransferase 5
HRASLS5 protein
Phospholipase A and acyltransferase 5 (Ca(2+)-independent N-acyltransferase) (iNAT) (EC 2.3.1.-, EC 3.1.1.32, EC 3.1.1.4) (H-rev107-like protein 5) (HRAS-like suppressor 5) (HRSL5)
SynonymsHRASLS5
HRLP5
DescriptionFUNCTION: Exhibits both phospholipase A1/2 and acyltransferase activities . Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids . Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE), which serves as precursor for N-acylethanolamines (NAEs) . .

AccessionsENST00000539221.5 [Q96KN8-2]
Q96KN8
H0YGT7
ENST00000540857.6 [Q96KN8-3]
ENST00000538712.1
ENST00000301790.4 [Q96KN8-1]
Q8NE88
ENST00000536887.5
F5H4Q3
H7BYL7
ENST00000394615.2