PIRT report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PIRT at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PIRT at tissue level.

III. Associated gene sets

GO_2001259Biological processpositive regulation of cation channel activity
GO_0048266Biological processbehavioral response to pain
GO_0009408Biological processresponse to heat
GO_0005886Cellular componentplasma membrane
GO_0005547Molecular functionphosphatidylinositol-3,4,5-trisphosphate binding
GO_1902936Molecular functionphosphatidylinositol bisphosphate binding
GO_0044325Molecular functiontransmembrane transporter binding

IV. Literature review

[source]
Gene namePIRT
Protein namePhosphoinositide-interacting protein
Synonyms
DescriptionFUNCTION: Regulatory subunit of TRPV1, a molecular sensor of noxious heat and capsaicin. Positively regulates TRPV1 channel activity via phosphatidylinositol 4,5-bisphosphate (PIP2). Binds various phosphoinositide, including phosphatidylinositol 4,5-bisphosphate (PIP2), but not phosphatidylinositol (PI) (By similarity). .

AccessionsENST00000580256.3
P0C851