PIP5KL1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PIP5KL1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PIP5KL1 at tissue level.

III. Associated gene sets

GO_0030336Biological processnegative regulation of cell migration
GO_0001933Biological processnegative regulation of protein phosphorylation
GO_0046854Biological processphosphatidylinositol phosphate biosynthetic process
GO_0043065Biological processpositive regulation of apoptotic process
GO_0010917Biological processnegative regulation of mitochondrial membrane potential
GO_0042995Cellular componentcell projection
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0016308Molecular function1-phosphatidylinositol-4-phosphate 5-kinase activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene namePIP5KL1
Protein namePhosphatidylinositol 4-phosphate 5-kinase-like protein 1 (PI(4)P 5-kinase-like protein 1) (PtdIns(4)P-5-kinase-like protein 1) (EC 2.7.1.68)
Synonyms
DescriptionFUNCTION: May act as a scaffold to localize and regulate type I PI(4)P 5-kinases to specific compartments within the cell, where they generate PI(4,5)P2 for actin nucleation, signaling and scaffold protein recruitment and conversion to PI(3,4,5)P3. .

AccessionsENST00000300432.3 [Q5T9C9-2]
Q5T9C9
ENST00000388747.9 [Q5T9C9-1]