PIGW report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PIGW at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PIGW at tissue level.

III. Associated gene sets

GO_0016254Biological processpreassembly of GPI anchor in ER membrane
GO_0006505Biological processGPI anchor metabolic process
GO_0072659Biological processprotein localization to plasma membrane
GO_0006506Biological processGPI anchor biosynthetic process
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0008374Molecular functionO-acyltransferase activity
GO_0032216Molecular functionglucosaminyl-phosphatidylinositol O-acyltransferase activity

IV. Literature review

[source]
Gene namePIGW
Protein namePhosphatidylinositol glycan anchor biosynthesis class W (Phosphatidylinositol-glycan biosynthesis class W protein)
Phosphatidylinositol-glycan biosynthesis class W protein (PIG-W) (EC 2.3.-.-)
Synonyms
DescriptionFUNCTION: Required for the transport of GPI-anchored proteins to the plasma membrane . Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity). .

AccessionsQ7Z7B1
ENST00000619326.1
ENST00000632789.1
A0A087WWS9
ENST00000616581.2
ENST00000620233.1
ENST00000614443.2
ENST00000631508.1