PHKG1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PHKG1 at tissue level.

III. Associated gene sets

GO_0005975Biological processcarbohydrate metabolic process
GO_0005978Biological processglycogen biosynthetic process
GO_0005964Cellular componentphosphorylase kinase complex
GO_0005829Cellular componentcytosol
GO_0019899Molecular functionenzyme binding
GO_0005516Molecular functioncalmodulin binding
GO_0050321Molecular functiontau-protein kinase activity
GO_0106310Molecular functionprotein serine kinase activity
GO_0004689Molecular functionphosphorylase kinase activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene namePHKG1
Protein namePhosphorylase kinase catalytic subunit gamma 1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1, EC 2.7.11.26)
phosphorylase kinase (EC 2.7.11.19)
SynonymsPHKG
DescriptionFUNCTION: Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3 (By similarity). .

AccessionsENST00000395428.3
Q6NSZ4
ENST00000432123.5
C9JME8
ENST00000297373.7 [Q16816-1]
Q16816
F8WD25
ENST00000446428.5
ENST00000452681.6 [Q16816-2]
C9J2Q6