Insufficient scRNA-seq data for expression of PGA3 at single-cell level.
Insufficient scRNA-seq data for expression of PGA3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| stomach | 96% | 268444.16 | 343 / 359 | 19% | 38.98 | 54 / 286 |
| liver | 72% | 37.30 | 162 / 226 | 0% | 0 | 0 / 406 |
| spleen | 71% | 26.46 | 171 / 241 | 0% | 0 | 0 / 0 |
| pancreas | 67% | 29.04 | 219 / 328 | 0% | 0 | 0 / 178 |
| adrenal gland | 62% | 34.71 | 159 / 258 | 0% | 0.01 | 1 / 230 |
| bladder | 62% | 23.95 | 13 / 21 | 0% | 0 | 0 / 504 |
| esophagus | 53% | 260.19 | 763 / 1445 | 7% | 30.07 | 13 / 183 |
| uterus | 57% | 25.66 | 97 / 170 | 0% | 0.01 | 2 / 459 |
| intestine | 51% | 74.59 | 490 / 966 | 6% | 22.35 | 30 / 527 |
| ovary | 56% | 23.08 | 100 / 180 | 0% | 0.05 | 2 / 430 |
| prostate | 52% | 20.36 | 128 / 245 | 0% | 0 | 0 / 502 |
| kidney | 51% | 16.33 | 45 / 89 | 0% | 0.00 | 1 / 901 |
| thymus | 44% | 16.16 | 289 / 653 | 0% | 0 | 0 / 605 |
| adipose | 43% | 501.72 | 512 / 1204 | 0% | 0 | 0 / 0 |
| breast | 41% | 73.91 | 187 / 459 | 0% | 0.01 | 2 / 1118 |
| lung | 37% | 17.76 | 211 / 578 | 2% | 2.39 | 21 / 1155 |
| blood vessel | 36% | 16.65 | 486 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 36% | 13.41 | 335 / 929 | 0% | 0 | 0 / 0 |
| skin | 35% | 18.80 | 633 / 1809 | 0% | 0 | 0 / 472 |
| heart | 34% | 25.20 | 289 / 861 | 0% | 0 | 0 / 0 |
| muscle | 32% | 11.74 | 258 / 803 | 0% | 0 | 0 / 0 |
| brain | 29% | 10.80 | 777 / 2642 | 0% | 0.00 | 1 / 705 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006508 | Biological process | proteolysis |
| GO_0007586 | Biological process | digestion |
| GO_0097486 | Cellular component | multivesicular body lumen |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0004190 | Molecular function | aspartic-type endopeptidase activity |
| Gene name | PGA3 |
| Protein name | Pepsinogen A3 (Pepsinogen A4) Pepsin A-3 (EC 3.4.23.1) (Pepsinogen-3) Pepsinogen A3 |
| Synonyms | PGA4 |
| Description | FUNCTION: Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. |
| Accessions | ENST00000325558.11 F5H842 F5GXL4 P0DJD8 ENST00000537932.5 ENST00000543505.5 ENST00000543125.5 |