PFN3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PFN3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PFN3 at tissue level.

III. Associated gene sets

GO_0032233Biological processpositive regulation of actin filament bundle assembly
GO_0030036Biological processactin cytoskeleton organization
GO_0030833Biological processregulation of actin filament polymerization
GO_0005856Cellular componentcytoskeleton
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0003779Molecular functionactin binding
GO_0008289Molecular functionlipid binding

IV. Literature review

[source]
Gene namePFN3
Protein nameProfilin-3 (Profilin III)
Synonyms
DescriptionFUNCTION: Binds to actin and affects the structure of the cytoskeleton. Slightly reduces actin polymerization. Binds to poly-L-proline, phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol 4-phosphate (PtdIns(4)P). May be involved in spermatogenesis. .

AccessionsENST00000358571.3
P60673