PDE4C report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PDE4C at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PDE4C at tissue level.

III. Associated gene sets

GO_0019933Biological processcAMP-mediated signaling
GO_0006198Biological processcAMP catabolic process
GO_0005615Cellular componentextracellular space
GO_0005929Cellular componentcilium
GO_0005829Cellular componentcytosol
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005634Cellular componentnucleus
GO_0047555Molecular function3',5'-cyclic-GMP phosphodiesterase activity
GO_0004115Molecular function3',5'-cyclic-AMP phosphodiesterase activity
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene namePDE4C
Protein namePDE4C [amino acids 597-712]
Phosphodiesterase 4C
3',5'-cyclic-AMP phosphodiesterase 4C (EC 3.1.4.53) (DPDE1) (PDE21) (cAMP-specific phosphodiesterase 4C)
3',5'-cyclic-AMP phosphodiesterase (EC 3.1.4.53)
Phosphodiesterase (EC 3.1.4.-)
SynonymsDPDE1
hCG_36766
DescriptionFUNCTION: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. .

AccessionsO43850
Q9UPJ5
A0A2R9YJK9
ENST00000539010.5
ENST00000598111.7
ENST00000447275.7 [Q08493-2]
O76105
ENST00000594465.7 [Q08493-1]
U3KPR3
Q08493
ENST00000595343.5
M0R1P5
ENST00000599188.5
V9GYP2
ENST00000262805.17 [Q08493-3]
Q2VPB9
O43849
ENST00000599754.1
ENST00000594617.7 [Q08493-1]
O43851
Q32MM7
B7Z6T1
ENST00000610023.1
ENST00000593594.1
O76104
U3KPR4
Q9P1U3