PCDH12 | OmnibusX

Name	Number of supported studies	Average coverage
endothelial cell	9 studies	24% ± 12%	Explore
capillary endothelial cell	6 studies	28% ± 13%	Explore
glomerular endothelial cell	3 studies	19% ± 1%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of PCDH12 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	2287.96	653 / 653	98%	17.67	590 / 605
breast	100%	1645.40	459 / 459	97%	12.15	1086 / 1118
adrenal gland	100%	1372.31	258 / 258	93%	14.53	214 / 230
lung	100%	3715.66	578 / 578	85%	7.68	984 / 1155
kidney	100%	1661.24	89 / 89	81%	28.49	731 / 901
brain	84%	420.73	2229 / 2642	96%	11.26	674 / 705
stomach	95%	513.52	341 / 359	79%	6.40	226 / 286
intestine	99%	666.13	959 / 966	74%	5.24	389 / 527
bladder	100%	872.24	21 / 21	72%	5.54	364 / 504
ovary	99%	540.21	178 / 180	60%	3.41	258 / 430
uterus	100%	895.53	170 / 170	53%	4.05	243 / 459
esophagus	84%	543.09	1213 / 1445	67%	4.93	123 / 183
pancreas	56%	206.98	183 / 328	94%	8.87	168 / 178
liver	61%	289.83	138 / 226	85%	7.07	346 / 406
prostate	98%	693.71	241 / 245	46%	2.39	231 / 502
skin	64%	291.50	1154 / 1809	79%	6.55	373 / 472
spleen	100%	4697.82	241 / 241	0%	0	0 / 0
adipose	100%	1791.89	1203 / 1204	0%	0	0 / 0
heart	100%	1323.45	857 / 861	0%	0	0 / 0
blood vessel	90%	599.05	1199 / 1335	0%	0	0 / 0
muscle	77%	307.28	615 / 803	0%	0	0 / 0
lymph node	0%	0	0 / 0	66%	3.30	19 / 29
tonsil	0%	0	0 / 0	62%	3.58	28 / 45
eye	0%	0	0 / 0	60%	2.83	48 / 80
peripheral blood	9%	26.64	88 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0008038	Biological process	neuron recognition
GO_0060711	Biological process	labyrinthine layer development
GO_0007156	Biological process	homophilic cell adhesion via plasma membrane adhesion molecules
GO_0007155	Biological process	cell adhesion
GO_0016339	Biological process	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO_0005977	Biological process	glycogen metabolic process
GO_0005911	Cellular component	cell-cell junction
GO_0070062	Cellular component	extracellular exosome
GO_0005886	Cellular component	plasma membrane
GO_0005509	Molecular function	calcium ion binding

Gene name	PCDH12
Protein name	PCDH12 protein Protocadherin 12 Protocadherin-12 (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cad-2) (VE-cadherin-2) [Cleaved into: Protocadherin-12, secreted form]
Synonyms	UNQ395/PRO731
Description	FUNCTION: Cellular adhesion molecule that may play an important role in cell-cell interactions at interendothelial junctions (By similarity). Acts as a regulator of cell migration, probably via increasing cell-cell adhesion . Promotes homotypic calcium-dependent aggregation and adhesion and clusters at intercellular junctions (By similarity). Unable to bind to catenins, weakly associates with the cytoskeleton (By similarity). .
Accessions	ENST00000231484.4 Q8IUP8 E5RJD4 ENST00000510041.1 Q9NPG4 Q7Z738

PCDH12 report