PANX3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PANX3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PANX3 at tissue level.

III. Associated gene sets

GO_0006812Biological processmonoatomic cation transport
GO_0070588Biological processcalcium ion transmembrane transport
GO_0032732Biological processpositive regulation of interleukin-1 production
GO_0007267Biological processcell-cell signaling
GO_0001649Biological processosteoblast differentiation
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005886Cellular componentplasma membrane
GO_0005921Cellular componentgap junction
GO_0055077Molecular functiongap junction hemi-channel activity
GO_0005262Molecular functioncalcium channel activity
GO_0022829Molecular functionwide pore channel activity
GO_0005198Molecular functionstructural molecule activity

IV. Literature review

[source]
Gene namePANX3
Protein namePannexin-3
Synonyms
DescriptionFUNCTION: Regulator of osteoblast differentiation by functionning as a Ca(2+) channel in the endoplasmic reticulum which regulates calmodulin (CaM) pathways. Allows ATP release into the extracellular space and activation or purinergic receptors. .

AccessionsQ96QZ0
ENST00000284288.3