I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 32% ± 11% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 32% ± 11% |
Insufficient scRNA-seq data for expression of PANX2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 99% | 1391.00 | 645 / 653 | 91% | 10.63 | 548 / 605 |
| prostate | 89% | 741.39 | 219 / 245 | 99% | 13.15 | 495 / 502 |
| brain | 98% | 3524.73 | 2597 / 2642 | 88% | 10.70 | 617 / 705 |
| liver | 92% | 754.37 | 208 / 226 | 78% | 19.35 | 316 / 406 |
| ovary | 81% | 518.71 | 145 / 180 | 70% | 7.56 | 301 / 430 |
| lung | 72% | 320.91 | 418 / 578 | 77% | 22.29 | 891 / 1155 |
| bladder | 38% | 194.76 | 8 / 21 | 58% | 11.75 | 292 / 504 |
| kidney | 76% | 397.85 | 68 / 89 | 17% | 2.21 | 157 / 901 |
| breast | 32% | 140.93 | 148 / 459 | 58% | 6.28 | 650 / 1118 |
| esophagus | 28% | 236.74 | 398 / 1445 | 58% | 21.96 | 106 / 183 |
| uterus | 22% | 128.22 | 38 / 170 | 59% | 8.13 | 270 / 459 |
| peripheral blood | 78% | 1179.47 | 723 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 71% | 9.41 | 32 / 45 |
| adrenal gland | 15% | 66.16 | 39 / 258 | 56% | 4.59 | 128 / 230 |
| eye | 0% | 0 | 0 / 0 | 61% | 6.20 | 49 / 80 |
| spleen | 55% | 267.76 | 133 / 241 | 0% | 0 | 0 / 0 |
| skin | 12% | 43.58 | 226 / 1809 | 30% | 3.13 | 140 / 472 |
| pancreas | 10% | 39.27 | 32 / 328 | 30% | 2.56 | 54 / 178 |
| blood vessel | 16% | 65.93 | 218 / 1335 | 0% | 0 | 0 / 0 |
| stomach | 1% | 3.40 | 4 / 359 | 12% | 1.21 | 35 / 286 |
| adipose | 11% | 38.28 | 129 / 1204 | 0% | 0 | 0 / 0 |
| intestine | 0% | 0.56 | 2 / 966 | 10% | 0.95 | 55 / 527 |
| muscle | 4% | 14.12 | 30 / 803 | 0% | 0 | 0 / 0 |
| heart | 1% | 1.79 | 5 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006812 | Biological process | monoatomic cation transport |
| GO_0034220 | Biological process | monoatomic ion transmembrane transport |
| GO_0002931 | Biological process | response to ischemia |
| GO_0032732 | Biological process | positive regulation of interleukin-1 production |
| GO_0007267 | Biological process | cell-cell signaling |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0005198 | Molecular function | structural molecule activity |
| GO_0022829 | Molecular function | wide pore channel activity |
| GO_0055077 | Molecular function | gap junction hemi-channel activity |
| Gene name | PANX2 |
| Protein name | Pannexin-2 Pannexin 2 Pannexin PANX2 protein |
| Synonyms | hCG_31860 PANX |
| Description | FUNCTION: Ion channel with a slight anion preference . Also able to release ATP . Plays a role in regulating neurogenesis and apoptosis in keratinocytes (By similarity). . FUNCTION: Structural component of the gap junctions and the hemichannels. . |
| Accessions | B3KTT7 ENST00000159647.9 [Q96RD6-1] Q96RD6 ENST00000402472.2 Q495U3 ENST00000395842.3 [Q96RD6-3] F8W8Y4 |
