PANK2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051881Biological processregulation of mitochondrial membrane potential
GO_0001525Biological processangiogenesis
GO_0016310Biological processphosphorylation
GO_0090207Biological processregulation of triglyceride metabolic process
GO_0007005Biological processmitochondrion organization
GO_0019217Biological processregulation of fatty acid metabolic process
GO_0009060Biological processaerobic respiration
GO_0015937Biological processcoenzyme A biosynthetic process
GO_0015939Biological processpantothenate metabolic process
GO_1904251Biological processregulation of bile acid metabolic process
GO_0007286Biological processspermatid development
GO_0005758Cellular componentmitochondrial intermembrane space
GO_0005829Cellular componentcytosol
GO_0005739Cellular componentmitochondrion
GO_0005634Cellular componentnucleus
GO_0004594Molecular functionpantothenate kinase activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene namePANK2
Protein namePantothenate kinase 2, mitochondrial (hPanK2) (EC 2.7.1.33) (Pantothenic acid kinase 2) [Cleaved into: Pantothenate kinase 2, mitochondrial intermediate form (iPanK2); Pantothenate kinase 2, mitochondrial mature form (mPanK2)]
PANK2 protein
Pantothenate kinase 2
SynonymsC20orf48
DescriptionFUNCTION: [Isoform 1]: Mitochondrial isoform that catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis . Required for angiogenic activity of umbilical vein of endothelial cells (HUVEC) . .; FUNCTION: [Isoform 4]: Cytoplasmic isoform that catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis. .

AccessionsENST00000643504.2
A0A2R8YF29
ENST00000495692.5
A0A2R8YFI4
Q52M85
ENST00000336066.8
Q6P1K9
ENST00000610179.7 [Q9BZ23-4]
V9GYZ0
ENST00000497424.5 [Q9BZ23-2]
ENST00000621507.1 [Q9BZ23-2]
Q9BZ23
ENST00000646394.1
ENST00000316562.9 [Q9BZ23-1]
A4FU43
V9GYH1