Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 10 studies | 24% ± 5% | |
microglial cell | 8 studies | 27% ± 10% | |
macrophage | 7 studies | 25% ± 5% | |
classical monocyte | 5 studies | 23% ± 5% | |
epithelial cell | 5 studies | 31% ± 9% | |
fibroblast | 5 studies | 23% ± 5% | |
ciliated cell | 5 studies | 20% ± 4% | |
GABAergic neuron | 5 studies | 34% ± 10% | |
astrocyte | 5 studies | 27% ± 7% | |
non-classical monocyte | 4 studies | 27% ± 8% | |
glutamatergic neuron | 4 studies | 49% ± 8% | |
neuron | 4 studies | 34% ± 13% | |
conventional dendritic cell | 3 studies | 28% ± 8% | |
hematopoietic precursor cell | 3 studies | 19% ± 0% | |
myeloid cell | 3 studies | 19% ± 3% | |
lymphocyte | 3 studies | 20% ± 2% | |
oligodendrocyte precursor cell | 3 studies | 29% ± 9% | |
dendritic cell | 3 studies | 29% ± 8% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 24% ± 10% | |
monocyte | 3 studies | 23% ± 3% | |
basal cell | 3 studies | 30% ± 5% | |
interneuron | 3 studies | 39% ± 16% | |
natural killer cell | 3 studies | 20% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1644.64 | 1445 / 1445 | 100% | 11.88 | 183 / 183 |
intestine | 100% | 1366.57 | 966 / 966 | 100% | 10.60 | 527 / 527 |
lung | 100% | 1538.76 | 578 / 578 | 100% | 12.85 | 1155 / 1155 |
ovary | 100% | 1239.94 | 180 / 180 | 100% | 12.41 | 430 / 430 |
thymus | 100% | 1466.08 | 653 / 653 | 100% | 15.90 | 605 / 605 |
uterus | 100% | 1384.95 | 170 / 170 | 100% | 14.62 | 459 / 459 |
breast | 100% | 1375.67 | 459 / 459 | 100% | 15.12 | 1117 / 1118 |
bladder | 100% | 1343.00 | 21 / 21 | 100% | 12.34 | 503 / 504 |
brain | 100% | 1457.92 | 2636 / 2642 | 100% | 14.39 | 705 / 705 |
skin | 100% | 1491.93 | 1808 / 1809 | 100% | 17.25 | 471 / 472 |
stomach | 100% | 1010.60 | 359 / 359 | 100% | 10.58 | 285 / 286 |
prostate | 100% | 1363.72 | 245 / 245 | 100% | 10.76 | 500 / 502 |
liver | 100% | 667.99 | 226 / 226 | 99% | 6.79 | 401 / 406 |
kidney | 100% | 1180.34 | 89 / 89 | 99% | 9.45 | 888 / 901 |
adrenal gland | 100% | 1627.83 | 258 / 258 | 97% | 9.07 | 224 / 230 |
pancreas | 98% | 638.48 | 320 / 328 | 99% | 10.71 | 177 / 178 |
adipose | 100% | 1461.87 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1722.25 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 17.40 | 29 / 29 |
spleen | 100% | 1846.93 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 15.74 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.84 | 1 / 1 |
muscle | 100% | 749.76 | 800 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 1774.32 | 918 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 11.95 | 79 / 80 |
heart | 97% | 679.02 | 837 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0051881 | Biological process | regulation of mitochondrial membrane potential |
GO_0001525 | Biological process | angiogenesis |
GO_0016310 | Biological process | phosphorylation |
GO_0090207 | Biological process | regulation of triglyceride metabolic process |
GO_0007005 | Biological process | mitochondrion organization |
GO_0019217 | Biological process | regulation of fatty acid metabolic process |
GO_0009060 | Biological process | aerobic respiration |
GO_0015937 | Biological process | coenzyme A biosynthetic process |
GO_0015939 | Biological process | pantothenate metabolic process |
GO_1904251 | Biological process | regulation of bile acid metabolic process |
GO_0007286 | Biological process | spermatid development |
GO_0005758 | Cellular component | mitochondrial intermembrane space |
GO_0005829 | Cellular component | cytosol |
GO_0005739 | Cellular component | mitochondrion |
GO_0005634 | Cellular component | nucleus |
GO_0004594 | Molecular function | pantothenate kinase activity |
GO_0005524 | Molecular function | ATP binding |
Gene name | PANK2 |
Protein name | Pantothenate kinase 2, mitochondrial (hPanK2) (EC 2.7.1.33) (Pantothenic acid kinase 2) [Cleaved into: Pantothenate kinase 2, mitochondrial intermediate form (iPanK2); Pantothenate kinase 2, mitochondrial mature form (mPanK2)] PANK2 protein Pantothenate kinase 2 |
Synonyms | C20orf48 |
Description | FUNCTION: [Isoform 1]: Mitochondrial isoform that catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis . Required for angiogenic activity of umbilical vein of endothelial cells (HUVEC) . .; FUNCTION: [Isoform 4]: Cytoplasmic isoform that catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis. . |
Accessions | ENST00000643504.2 A0A2R8YF29 ENST00000495692.5 A0A2R8YFI4 Q52M85 ENST00000336066.8 Q6P1K9 ENST00000610179.7 [Q9BZ23-4] V9GYZ0 ENST00000497424.5 [Q9BZ23-2] ENST00000621507.1 [Q9BZ23-2] Q9BZ23 ENST00000646394.1 ENST00000316562.9 [Q9BZ23-1] A4FU43 V9GYH1 |