PAH report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
hepatocyte	6 studies	73% ± 23%	Explore
epithelial cell of proximal tubule	6 studies	51% ± 14%	Explore
endothelial cell	3 studies	29% ± 9%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
liver	4 studies	44% ± 22%	Explore
kidney	3 studies	23% ± 4%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	49397.32	226 / 226	98%	248.47	398 / 406
adrenal gland	96%	839.23	248 / 258	71%	6.88	163 / 230
pancreas	99%	800.79	324 / 328	54%	4.15	96 / 178
kidney	100%	12224.78	89 / 89	50%	16.86	448 / 901
brain	87%	189.68	2293 / 2642	28%	0.67	194 / 705
prostate	48%	96.74	118 / 245	18%	1.05	88 / 502
thymus	35%	26.09	228 / 653	4%	0.11	27 / 605
breast	11%	9.11	49 / 459	22%	0.99	249 / 1118
intestine	2%	1.45	19 / 966	29%	1.59	154 / 527
stomach	1%	0.38	2 / 359	30%	1.54	87 / 286
bladder	5%	2.29	1 / 21	15%	0.61	75 / 504
lung	1%	0.95	7 / 578	14%	1.57	162 / 1155
esophagus	1%	0.98	11 / 1445	10%	2.11	19 / 183
peripheral blood	9%	16.86	85 / 929	0%	0	0 / 0
ovary	7%	9.16	12 / 180	2%	0.03	8 / 430
tonsil	0%	0	0 / 0	7%	0.44	3 / 45
uterus	2%	1.59	3 / 170	3%	0.17	14 / 459
adipose	4%	11.43	54 / 1204	0%	0	0 / 0
skin	1%	1.34	14 / 1809	2%	0.05	10 / 472
spleen	1%	44.06	2 / 241	0%	0	0 / 0
blood vessel	1%	1.05	10 / 1335	0%	0	0 / 0
heart	1%	1.45	6 / 861	0%	0	0 / 0
muscle	0%	0.19	3 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1