OXCT2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of OXCT2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of OXCT2 at tissue level.

III. Associated gene sets

GO_0046952Biological processketone body catabolic process
GO_0046950Biological processcellular ketone body metabolic process
GO_0031514Cellular componentmotile cilium
GO_0005759Cellular componentmitochondrial matrix
GO_0005739Cellular componentmitochondrion
GO_0008260Molecular functionsuccinyl-CoA:3-oxo-acid CoA-transferase activity

IV. Literature review

[source]
Gene nameOXCT2
Protein nameSuccinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial (EC 2.8.3.5) (3-oxoacid CoA-transferase 2A) (Testis-specific succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-t)
OXCT2 protein
SynonymsFKSG25
DescriptionFUNCTION: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (By similarity). .

AccessionsENST00000327582.5
Q9BYC2
Q6INA3