Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| classical monocyte | 12 studies | 31% ± 12% | |
| alveolar macrophage | 8 studies | 21% ± 8% | |
| monocyte | 7 studies | 23% ± 6% | |
| non-classical monocyte | 7 studies | 25% ± 12% | |
| macrophage | 4 studies | 25% ± 9% | |
| conventional dendritic cell | 3 studies | 27% ± 8% | |
| myeloid cell | 3 studies | 20% ± 2% |
Insufficient scRNA-seq data for expression of OSCAR at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 2260.49 | 578 / 578 | 95% | 14.19 | 1101 / 1155 |
| breast | 89% | 152.90 | 407 / 459 | 96% | 9.36 | 1071 / 1118 |
| skin | 97% | 180.39 | 1746 / 1809 | 81% | 8.33 | 381 / 472 |
| uterus | 76% | 111.12 | 129 / 170 | 87% | 6.99 | 399 / 459 |
| brain | 62% | 115.05 | 1647 / 2642 | 92% | 8.27 | 649 / 705 |
| intestine | 75% | 108.46 | 728 / 966 | 78% | 5.99 | 411 / 527 |
| bladder | 81% | 170.90 | 17 / 21 | 72% | 7.02 | 364 / 504 |
| esophagus | 70% | 94.73 | 1017 / 1445 | 80% | 4.98 | 146 / 183 |
| ovary | 62% | 77.68 | 111 / 180 | 88% | 7.81 | 379 / 430 |
| thymus | 64% | 82.75 | 417 / 653 | 82% | 6.68 | 497 / 605 |
| kidney | 54% | 92.02 | 48 / 89 | 87% | 8.03 | 787 / 901 |
| prostate | 86% | 148.22 | 210 / 245 | 51% | 1.91 | 256 / 502 |
| stomach | 38% | 64.26 | 135 / 359 | 84% | 6.50 | 239 / 286 |
| pancreas | 25% | 41.65 | 83 / 328 | 92% | 14.32 | 163 / 178 |
| adrenal gland | 82% | 127.71 | 211 / 258 | 26% | 1.17 | 60 / 230 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 23.75 | 29 / 29 |
| spleen | 100% | 2332.55 | 241 / 241 | 0% | 0 | 0 / 0 |
| liver | 57% | 91.01 | 129 / 226 | 37% | 1.97 | 150 / 406 |
| adipose | 94% | 278.17 | 1132 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 8.07 | 42 / 45 |
| peripheral blood | 83% | 7036.05 | 772 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 73% | 191.95 | 979 / 1335 | 0% | 0 | 0 / 0 |
| heart | 52% | 77.68 | 451 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 25% | 0.85 | 20 / 80 |
| muscle | 4% | 3.91 | 35 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0038065 | Biological process | collagen-activated signaling pathway |
| GO_0030316 | Biological process | osteoclast differentiation |
| GO_0002764 | Biological process | immune response-regulating signaling pathway |
| GO_1904724 | Cellular component | tertiary granule lumen |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0035580 | Cellular component | specific granule lumen |
| GO_0038064 | Molecular function | collagen receptor activity |
| Gene name | OSCAR |
| Protein name | Osteoclast-associated immunoglobulin-like receptor (Osteoclast-associated receptor) (hOSCAR) (Polymeric immunoglobulin receptor 3) (PIgR-3) (PIgR3) (Poly-Ig receptor 3) Osteoclast-associated immunoglobulin-like receptor Osteoclast associated Ig-like receptor |
| Synonyms | |
| Description | FUNCTION: Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation. . |
| Accessions | ENST00000616461.4 [Q8IYS5-7] A0A0A0MRF2 ENST00000621506.4 [Q8IYS5-4] ENST00000614380.4 [Q8IYS5-7] ENST00000621284.4 [Q8IYS5-4] ENST00000611480.4 [Q8IYS5-1] ENST00000620283.4 [Q8IYS5-3] ENST00000610985.4 [Q8IYS5-7] ENST00000612406.4 [Q8IYS5-7] ENST00000611535.4 [Q8IYS5-2] A0A087X1R2 ENST00000358375.9 ENST00000618058.1 Q8IYS5 ENST00000616215.4 ENST00000620647.4 [Q8IYS5-1] ENST00000621788.4 [Q8IYS5-3] ENST00000622288.4 [Q8IYS5-3] ENST00000356532.7 ENST00000618710.4 [Q8IYS5-1] ENST00000611719.4 [Q8IYS5-4] ENST00000611918.4 [Q8IYS5-4] ENST00000621290.4 [Q8IYS5-3] ENST00000611715.4 [Q8IYS5-4] ENST00000610577.4 [Q8IYS5-7] ENST00000622275.1 ENST00000615745.1 ENST00000617622.4 [Q8IYS5-1] ENST00000622326.4 [Q8IYS5-1] ENST00000610915.4 [Q8IYS5-4] ENST00000351806.8 A0A087WV17 ENST00000614003.4 [Q8IYS5-1] ENST00000616227.4 [Q8IYS5-7] ENST00000616232.4 [Q8IYS5-4] ENST00000617187.4 [Q8IYS5-7] ENST00000617993.4 [Q8IYS5-7] ENST00000615074.4 [Q8IYS5-7] ENST00000619287.4 [Q8IYS5-6] A0A0G2JMM7 ENST00000617140.4 ENST00000617834.4 [Q8IYS5-3] ENST00000619631.4 [Q8IYS5-4] A0A0G2JNK2 ENST00000611143.4 [Q8IYS5-3] ENST00000611261.4 ENST00000617210.4 [Q8IYS5-3] ENST00000621328.4 [Q8IYS5-3] ENST00000613426.4 [Q8IYS5-1] A8MWV3 ENST00000622843.4 ENST00000616758.4 [Q8IYS5-1] ENST00000612953.4 [Q8IYS5-7] ENST00000611450.1 A0A0A0MR14 ENST00000611322.1 ENST00000612289.4 [Q8IYS5-1] ENST00000612543.1 ENST00000359649.8 ENST00000613814.1 [Q8IYS5-4] ENST00000611987.4 [Q8IYS5-3] ENST00000615546.4 [Q8IYS5-4] ENST00000391760.1 ENST00000611789.4 ENST00000614057.1 ENST00000613895.1 ENST00000619170.4 [Q8IYS5-3] ENST00000284648.10 ENST00000391761.5 |