OPTC report

I. Expression across cell types

Insufficient scRNA-seq data for expression of OPTC at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of OPTC at tissue level.

III. Associated gene sets

GO_0001525Biological processangiogenesis
GO_0030199Biological processcollagen fibril organization
GO_0060348Biological processbone development
GO_0061975Biological processarticular cartilage development
GO_0016525Biological processnegative regulation of angiogenesis
GO_0005576Cellular componentextracellular region
GO_0031012Cellular componentextracellular matrix
GO_0005201Molecular functionextracellular matrix structural constituent

IV. Literature review

[source]
Gene nameOPTC
Protein nameOpticin
Opticin (Oculoglycan)
SynonymsOPT
DescriptionFUNCTION: Inhibits angiogenesis in the vitreous humor of the eye, and therefore represses neovascularization (By similarity). Binds collagen fibrils (By similarity). May be involved in collagen fiber organization via regulation of other members of the small leucine-rich repeat proteoglycan superfamily (By similarity). .

AccessionsENST00000448911.1
Q5T2G3
Q66MN3
Q9UBM4
ENST00000367222.7