OCSTAMP report

I. Expression across cell types

Insufficient scRNA-seq data for expression of OCSTAMP at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of OCSTAMP at tissue level.

III. Associated gene sets

GO_0045672Biological processpositive regulation of osteoclast differentiation
GO_0071356Biological processcellular response to tumor necrosis factor
GO_0071391Biological processcellular response to estrogen stimulus
GO_0090290Biological processpositive regulation of osteoclast proliferation
GO_0072674Biological processmultinuclear osteoclast differentiation
GO_0034241Biological processpositive regulation of macrophage fusion
GO_0016020Cellular componentmembrane

IV. Literature review

[source]
Gene nameOCSTAMP
Protein nameOsteoclast stimulatory transmembrane protein (OC-STAMP)
SynonymsC20orf123
DescriptionFUNCTION: Probable cell surface receptor that plays a role in cellular fusion and cell differentiation. Cooperates with DCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Involved in osteoclast bone resorption. Promotes osteoclast differentiation and may play a role in the multinucleated osteoclast maturation (By similarity). .

AccessionsENST00000279028.3
Q9BR26