Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 4 studies | 20% ± 4% |
Insufficient scRNA-seq data for expression of NUDT7 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 316.01 | 226 / 226 | 97% | 6.88 | 392 / 406 |
kidney | 100% | 150.26 | 89 / 89 | 95% | 3.98 | 853 / 901 |
thymus | 100% | 160.60 | 651 / 653 | 95% | 2.96 | 573 / 605 |
adrenal gland | 100% | 310.97 | 258 / 258 | 92% | 4.39 | 211 / 230 |
intestine | 100% | 119.65 | 962 / 966 | 91% | 2.62 | 479 / 527 |
brain | 98% | 88.96 | 2577 / 2642 | 93% | 3.95 | 653 / 705 |
stomach | 99% | 81.72 | 356 / 359 | 85% | 2.37 | 242 / 286 |
prostate | 96% | 71.04 | 235 / 245 | 87% | 1.98 | 436 / 502 |
breast | 100% | 146.43 | 458 / 459 | 74% | 1.76 | 832 / 1118 |
pancreas | 96% | 62.18 | 314 / 328 | 77% | 1.53 | 137 / 178 |
ovary | 97% | 76.17 | 175 / 180 | 75% | 1.54 | 322 / 430 |
lung | 89% | 73.12 | 513 / 578 | 81% | 2.26 | 937 / 1155 |
uterus | 99% | 92.62 | 169 / 170 | 69% | 1.69 | 319 / 459 |
esophagus | 98% | 95.42 | 1423 / 1445 | 65% | 1.43 | 119 / 183 |
skin | 98% | 92.28 | 1775 / 1809 | 55% | 1.15 | 259 / 472 |
bladder | 95% | 102.90 | 20 / 21 | 57% | 1.58 | 286 / 504 |
spleen | 100% | 83.47 | 241 / 241 | 0% | 0 | 0 / 0 |
adipose | 100% | 170.16 | 1202 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 160.64 | 1330 / 1335 | 0% | 0 | 0 / 0 |
heart | 96% | 261.90 | 824 / 861 | 0% | 0 | 0 / 0 |
muscle | 92% | 62.31 | 739 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 88% | 2.30 | 70 / 80 |
tonsil | 0% | 0 | 0 / 0 | 80% | 1.89 | 36 / 45 |
lymph node | 0% | 0 | 0 / 0 | 72% | 2.20 | 21 / 29 |
peripheral blood | 49% | 30.35 | 458 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0050873 | Biological process | brown fat cell differentiation |
GO_0044580 | Biological process | butyryl-CoA catabolic process |
GO_2001294 | Biological process | malonyl-CoA catabolic process |
GO_0046356 | Biological process | acetyl-CoA catabolic process |
GO_0008150 | Biological process | biological_process |
GO_1902859 | Biological process | propionyl-CoA catabolic process |
GO_0036114 | Biological process | medium-chain fatty-acyl-CoA catabolic process |
GO_1902858 | Biological process | propionyl-CoA metabolic process |
GO_0009132 | Biological process | nucleoside diphosphate metabolic process |
GO_1901289 | Biological process | succinyl-CoA catabolic process |
GO_0015938 | Biological process | coenzyme A catabolic process |
GO_0005777 | Cellular component | peroxisome |
GO_0005829 | Cellular component | cytosol |
GO_0005782 | Cellular component | peroxisomal matrix |
GO_0140933 | Molecular function | 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity |
GO_0000287 | Molecular function | magnesium ion binding |
GO_0030145 | Molecular function | manganese ion binding |
GO_0030515 | Molecular function | snoRNA binding |
GO_0010945 | Molecular function | coenzyme A diphosphatase activity |
GO_0003674 | Molecular function | molecular_function |
Gene name | NUDT7 |
Protein name | Peroxisomal coenzyme A diphosphatase NUDT7 (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 7) (Nudix motif 7) Nudix hydrolase 7 |
Synonyms | |
Description | FUNCTION: Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (By similarity). Cleaves CoA, CoA esters and oxidized CoA with similar efficiencies (By similarity). Preferentially hydrolyzes medium-chain acyl-CoAs and bile acid-CoAs (By similarity). Has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester (By similarity). May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand (By similarity). Does not play a role in U8 snoRNA decapping activity (By similarity). Binds U8 snoRNA (By similarity). Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity). . |
Accessions | ENST00000437314.3 [P0C024-2] P0C024 H3BRQ8 ENST00000268533.9 [P0C024-1] ENST00000564085.5 [P0C024-3] ENST00000568787.5 ENST00000613075.4 H3BMZ7 A0A087WVP7 ENST00000563839.1 |