Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 6 studies | 27% ± 11% | |
| ciliated cell | 3 studies | 23% ± 1% | |
| glutamatergic neuron | 3 studies | 25% ± 7% | |
| dendritic cell | 3 studies | 20% ± 2% | |
| endothelial cell | 3 studies | 19% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 20% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1837.47 | 1445 / 1445 | 100% | 18.67 | 183 / 183 |
| ovary | 100% | 1946.94 | 180 / 180 | 100% | 21.26 | 430 / 430 |
| pancreas | 100% | 1473.59 | 328 / 328 | 100% | 26.67 | 178 / 178 |
| skin | 100% | 1741.83 | 1809 / 1809 | 100% | 28.10 | 472 / 472 |
| stomach | 100% | 1616.38 | 359 / 359 | 100% | 19.27 | 286 / 286 |
| uterus | 100% | 2040.12 | 170 / 170 | 100% | 28.94 | 459 / 459 |
| thymus | 100% | 2770.17 | 653 / 653 | 100% | 32.93 | 604 / 605 |
| lung | 100% | 2088.76 | 577 / 578 | 100% | 26.33 | 1155 / 1155 |
| liver | 100% | 2857.56 | 226 / 226 | 100% | 37.09 | 405 / 406 |
| intestine | 100% | 2561.08 | 966 / 966 | 100% | 21.19 | 525 / 527 |
| bladder | 100% | 1935.48 | 21 / 21 | 100% | 29.84 | 502 / 504 |
| prostate | 100% | 2468.46 | 245 / 245 | 100% | 25.43 | 500 / 502 |
| breast | 100% | 2111.08 | 459 / 459 | 100% | 31.58 | 1113 / 1118 |
| brain | 100% | 1354.83 | 2630 / 2642 | 100% | 26.70 | 705 / 705 |
| adrenal gland | 100% | 4936.79 | 258 / 258 | 99% | 24.63 | 228 / 230 |
| kidney | 100% | 2979.42 | 89 / 89 | 99% | 30.34 | 893 / 901 |
| adipose | 100% | 1966.25 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 25.33 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 32.65 | 29 / 29 |
| spleen | 100% | 2618.22 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 22.18 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 16.58 | 1 / 1 |
| blood vessel | 100% | 1873.49 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 1312.25 | 854 / 861 | 0% | 0 | 0 / 0 |
| muscle | 99% | 1018.84 | 794 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 1590.36 | 915 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0043605 | Biological process | amide catabolic process |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0005634 | Cellular component | nucleus |
| GO_0110050 | Molecular function | deaminated glutathione amidase activity |
| Gene name | NIT1 |
| Protein name | Deaminated glutathione amidase (dGSH amidase) (EC 3.5.1.128) (Nitrilase homolog 1) |
| Synonyms | |
| Description | FUNCTION: Catalyzes the hydrolysis of the amide bond in N-(4-oxoglutarate)-L-cysteinylglycine (deaminated glutathione), a metabolite repair reaction to dispose of the harmful deaminated glutathione. Plays a role in cell growth and apoptosis: loss of expression promotes cell growth, resistance to DNA damage stress and increased incidence to NMBA-induced tumors. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. . |
| Accessions | Q86X76 ENST00000368008.5 [Q86X76-5] ENST00000368009.7 [Q86X76-1] ENST00000392190.9 [Q86X76-2] ENST00000368007.8 [Q86X76-4] |
