NEURL2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of NEURL2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NEURL2 at tissue level.

III. Associated gene sets

GO_0035556Biological processintracellular signal transduction
GO_0016567Biological processprotein ubiquitination
GO_0005829Cellular componentcytosol
GO_0061630Molecular functionubiquitin protein ligase activity

IV. Literature review

[source]
Gene nameNEURL2
Protein nameNeuralized-like protein 2
Neuralized E3 ubiquitin protein ligase 2
SynonymsC20orf163
DescriptionFUNCTION: Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By similarity). .

AccessionsQ9BR09
ENST00000372518.5
H0YGA6
ENST00000545238.1