Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 14 studies | 24% ± 5% | |
alveolar macrophage | 8 studies | 40% ± 12% | |
glutamatergic neuron | 8 studies | 47% ± 24% | |
myeloid cell | 6 studies | 28% ± 21% | |
GABAergic neuron | 5 studies | 47% ± 18% | |
cardiac muscle cell | 4 studies | 38% ± 3% | |
ciliated cell | 4 studies | 27% ± 7% | |
astrocyte | 4 studies | 29% ± 10% | |
monocyte | 4 studies | 30% ± 15% | |
neuron | 3 studies | 29% ± 3% | |
epithelial cell | 3 studies | 34% ± 11% | |
retinal cone cell | 3 studies | 19% ± 2% | |
pancreatic ductal cell | 3 studies | 46% ± 20% | |
interneuron | 3 studies | 39% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 1166.57 | 89 / 89 | 99% | 68.14 | 890 / 901 |
lung | 99% | 1402.51 | 573 / 578 | 97% | 38.87 | 1126 / 1155 |
stomach | 96% | 769.12 | 343 / 359 | 99% | 41.17 | 283 / 286 |
breast | 97% | 668.80 | 444 / 459 | 92% | 25.37 | 1033 / 1118 |
prostate | 99% | 609.86 | 242 / 245 | 90% | 20.46 | 453 / 502 |
esophagus | 91% | 461.50 | 1311 / 1445 | 97% | 45.92 | 178 / 183 |
intestine | 86% | 699.37 | 833 / 966 | 98% | 36.50 | 516 / 527 |
pancreas | 89% | 574.56 | 293 / 328 | 94% | 30.76 | 167 / 178 |
bladder | 90% | 492.67 | 19 / 21 | 92% | 26.77 | 462 / 504 |
brain | 99% | 2368.34 | 2607 / 2642 | 79% | 15.06 | 555 / 705 |
thymus | 97% | 508.56 | 634 / 653 | 78% | 10.92 | 474 / 605 |
uterus | 91% | 404.88 | 154 / 170 | 82% | 26.52 | 375 / 459 |
adrenal gland | 100% | 2219.03 | 258 / 258 | 68% | 11.41 | 156 / 230 |
ovary | 50% | 176.46 | 90 / 180 | 91% | 21.61 | 390 / 430 |
skin | 71% | 739.59 | 1284 / 1809 | 60% | 10.35 | 285 / 472 |
spleen | 97% | 844.16 | 234 / 241 | 0% | 0 | 0 / 0 |
adipose | 97% | 755.33 | 1166 / 1204 | 0% | 0 | 0 / 0 |
heart | 95% | 1469.43 | 818 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 93% | 27.36 | 42 / 45 |
muscle | 91% | 529.32 | 728 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 90% | 471.72 | 1199 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 86% | 21.47 | 25 / 29 |
liver | 26% | 93.94 | 59 / 226 | 28% | 10.91 | 113 / 406 |
peripheral blood | 50% | 275.50 | 464 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 3% | 0.28 | 2 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006805 | Biological process | xenobiotic metabolic process |
GO_0034383 | Biological process | low-density lipoprotein particle clearance |
GO_0046485 | Biological process | ether lipid metabolic process |
GO_0016042 | Biological process | lipid catabolic process |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0004771 | Molecular function | sterol esterase activity |
GO_0017171 | Molecular function | serine hydrolase activity |
GO_0042301 | Molecular function | phosphate ion binding |
GO_0047378 | Molecular function | acetylalkylglycerol acetylhydrolase activity |
Gene name | NCEH1 |
Protein name | Neutral cholesterol ester hydrolase 1 (EC 3.1.1.71) (Acetylalkylglycerol acetylhydrolase) (Arylacetamide deacetylase-like 1) Neutral cholesterol ester hydrolase 1 Neutral cholesterol ester hydrolase 1 (NCEH) (EC 3.1.1.-) (Acetylalkylglycerol acetylhydrolase) (2-acetyl MAGE hydrolase) (EC 3.1.1.71) (Arylacetamide deacetylase-like 1) |
Synonyms | AADACL1 KIAA1363 |
Description | FUNCTION: Hydrolyzes 2-acetyl monoalkylglycerol ether (1-O-alkyl-2-acetyl-sn-glycerol), the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor . May be responsible for the hydrolysis of cholesterol esters (such as cholesteryl (9Z-octadecenoate)) in macrophages (By similarity). Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds (By similarity). May contribute to cancer pathogenesis by promoting tumor cell migration . . |
Accessions | ENST00000424772.2 ENST00000543711.5 [Q6PIU2-3] ENST00000421723.2 Q6PIU2 ENST00000475381.7 [Q6PIU2-1] A0A0A0MTJ9 ENST00000538775.5 F8WE33 H7C046 |