Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 11 studies | 36% ± 16% | |
endothelial cell | 5 studies | 27% ± 10% | |
hepatocyte | 5 studies | 53% ± 19% | |
epithelial cell | 4 studies | 20% ± 5% | |
GABAergic neuron | 3 studies | 33% ± 4% | |
glutamatergic neuron | 3 studies | 45% ± 4% | |
ependymal cell | 3 studies | 39% ± 16% | |
oligodendrocyte | 3 studies | 19% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 2402.63 | 245 / 245 | 100% | 29.76 | 502 / 502 |
brain | 100% | 2765.85 | 2641 / 2642 | 100% | 49.78 | 705 / 705 |
liver | 100% | 11826.11 | 226 / 226 | 100% | 81.67 | 405 / 406 |
uterus | 100% | 2143.95 | 170 / 170 | 100% | 22.61 | 457 / 459 |
breast | 100% | 1905.44 | 459 / 459 | 100% | 26.15 | 1113 / 1118 |
ovary | 100% | 2358.08 | 180 / 180 | 100% | 14.86 | 428 / 430 |
lung | 99% | 1453.24 | 575 / 578 | 99% | 18.38 | 1148 / 1155 |
pancreas | 100% | 2375.86 | 328 / 328 | 98% | 13.30 | 175 / 178 |
bladder | 100% | 4893.81 | 21 / 21 | 98% | 20.68 | 494 / 504 |
esophagus | 100% | 2302.61 | 1445 / 1445 | 98% | 16.44 | 179 / 183 |
stomach | 100% | 2166.99 | 359 / 359 | 98% | 16.35 | 279 / 286 |
thymus | 100% | 2055.87 | 653 / 653 | 98% | 14.34 | 590 / 605 |
intestine | 100% | 2113.01 | 966 / 966 | 97% | 16.96 | 513 / 527 |
kidney | 100% | 1574.18 | 89 / 89 | 97% | 17.12 | 874 / 901 |
adrenal gland | 100% | 3011.30 | 258 / 258 | 90% | 12.52 | 206 / 230 |
skin | 100% | 1428.96 | 1806 / 1809 | 88% | 11.89 | 417 / 472 |
adipose | 100% | 1768.55 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2762.68 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 1719.91 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1261.19 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.12 | 1 / 1 |
tonsil | 0% | 0 | 0 / 0 | 98% | 21.34 | 44 / 45 |
heart | 96% | 1354.28 | 827 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 90% | 11.81 | 26 / 29 |
eye | 0% | 0 | 0 / 0 | 60% | 5.58 | 48 / 80 |
peripheral blood | 29% | 230.76 | 268 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0019674 | Biological process | NAD metabolic process |
GO_0006741 | Biological process | NADP biosynthetic process |
GO_0005759 | Cellular component | mitochondrial matrix |
GO_0005739 | Cellular component | mitochondrion |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0005524 | Molecular function | ATP binding |
GO_0003951 | Molecular function | NAD+ kinase activity |
Gene name | NADK2 |
Protein name | NAD kinase 2, mitochondrial NAD kinase 2, mitochondrial (EC 2.7.1.23) (NAD kinase domain-containing protein 1, mitochondrial) NAD kinase 2, mitochondrial (EC 2.7.1.23) (Mitochondrial NAD kinase) (NAD kinase domain-containing protein 1, mitochondrial) |
Synonyms | NADKD1 MNADK C5orf33 |
Description | FUNCTION: Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. Also has weak NADH kinase activity in vitro; however NADH kinase activity is much weaker than the NAD(+) kinase activity and may not be relevant in vivo. . FUNCTION: Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. . |
Accessions | D6RHI4 ENST00000511088.1 Q4G0N4 ENST00000514504.5 [Q4G0N4-2] B7Z8V7 ENST00000397338.5 [Q4G0N4-3] ENST00000617628.4 ENST00000502355.5 A0A0C4DGV3 ENST00000282512.7 [Q4G0N4-3] H0Y9H7 ENST00000506945.5 ENST00000381937.9 [Q4G0N4-1] |