NAALADL1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NAALADL1 at tissue level.

III. Associated gene sets

GO_0006508Biological processproteolysis
GO_0043171Biological processpeptide catabolic process
GO_0016324Cellular componentapical plasma membrane
GO_0016020Cellular componentmembrane
GO_0042803Molecular functionprotein homodimerization activity
GO_0008233Molecular functionpeptidase activity
GO_0004180Molecular functioncarboxypeptidase activity
GO_0005509Molecular functioncalcium ion binding
GO_0008270Molecular functionzinc ion binding
GO_0008237Molecular functionmetallopeptidase activity
GO_0004177Molecular functionaminopeptidase activity

IV. Literature review

[source]
Gene nameNAALADL1
Protein nameN-acetylated alpha-linked acidic dipeptidase like 1
Aminopeptidase NAALADL1 (EC 3.4.11.-) (100 kDa ileum brush border membrane protein) (I100) (Ileal dipeptidylpeptidase) (N-acetylated-alpha-linked acidic dipeptidase-like protein) (NAALADase L)
SynonymsNAALADASEL
NAALADL
DescriptionFUNCTION: Aminopeptidase with broad substrate specificity. Has lower activity with substrates that have Asp or Glu in the P2' position, or Pro in the P3' position. Lacks activity with substrates that have both Pro in the P3' position and Asp or Glu in the P2' position . Lacks carboxypeptidase activity. Lacks dipeptidyl-peptidase IV type activity . .

AccessionsENST00000532802.5
ENST00000356632.7
H0YEI8
C9JFW8
ENST00000530995.5
E9PKR0
ENST00000533842.5
ENST00000358658.8 [Q9UQQ1-1]
ENST00000533753.5
E9PLR8
E9PJQ1
ENST00000526516.5
Q9UQQ1
ENST00000526799.5
E9PIU1
H0YDS5
ENST00000340252.8 [Q9UQQ1-4]
ENST00000532450.5
ENST00000530139.2
E9PKW7
E9PKG8
E9PII9
ENST00000355721.7 [Q9UQQ1-2]
E9PRC7
ENST00000533340.5
ENST00000528884.5