MYMK report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MYMK at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MYMK at tissue level.

III. Associated gene sets

GO_1904206Biological processpositive regulation of skeletal muscle hypertrophy
GO_0007520Biological processmyoblast fusion
GO_0014905Biological processmyoblast fusion involved in skeletal muscle regeneration
GO_0007517Biological processmuscle organ development
GO_0045026Biological processplasma membrane fusion
GO_0000139Cellular componentGolgi membrane
GO_0005886Cellular componentplasma membrane

IV. Literature review

[source]
Gene nameMYMK
Protein nameProtein myomaker (Myoblast fusion maker) (Transmembrane protein 226) (Transmembrane protein 8C)
SynonymsTMEM8C
TMEM226
DescriptionFUNCTION: Myoblast-specific protein that mediates myoblast fusion, an essential step for the formation of multi-nucleated muscle fibers . Actively participates in the membrane fusion reaction by mediating the mixing of cell membrane lipids (hemifusion) upstream of MYMX. Acts independently of MYMX (By similarity). Involved in skeletal muscle regeneration in response to injury by mediating the fusion of satellite cells, a population of muscle stem cells, with injured myofibers (By similarity). Also involved in skeletal muscle hypertrophy, probably by mediating the fusion of satellite cells with myofibers (By similarity). .

AccessionsENST00000339996.4
A6NI61