I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| erythrocyte | 7 studies | 50% ± 20% | |
| retinal cone cell | 6 studies | 57% ± 25% | |
| erythroblast | 4 studies | 53% ± 20% | |
| cardiac muscle cell | 3 studies | 48% ± 20% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| erythrocyte | 7 studies | 50% ± 20% | |
| retinal cone cell | 6 studies | 57% ± 25% | |
| erythroblast | 4 studies | 53% ± 20% | |
| cardiac muscle cell | 3 studies | 48% ± 20% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| liver | 3 studies | 46% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 98% | 413.38 | 639 / 653 | 86% | 34.98 | 518 / 605 |
| heart | 100% | 79135.76 | 858 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 84% | 1505.46 | 783 / 929 | 0% | 0 | 0 / 0 |
| kidney | 12% | 12.58 | 11 / 89 | 47% | 0.95 | 421 / 901 |
| lung | 38% | 273.75 | 220 / 578 | 8% | 0.15 | 97 / 1155 |
| spleen | 46% | 78.43 | 110 / 241 | 0% | 0 | 0 / 0 |
| stomach | 34% | 65.13 | 121 / 359 | 12% | 0.22 | 34 / 286 |
| pancreas | 1% | 1.33 | 2 / 328 | 45% | 0.83 | 80 / 178 |
| adipose | 34% | 48.91 | 407 / 1204 | 0% | 0 | 0 / 0 |
| breast | 19% | 67.60 | 87 / 459 | 12% | 0.20 | 135 / 1118 |
| bladder | 19% | 19.86 | 4 / 21 | 9% | 0.30 | 44 / 504 |
| adrenal gland | 2% | 2.40 | 5 / 258 | 21% | 1.13 | 48 / 230 |
| uterus | 5% | 4.89 | 9 / 170 | 16% | 27.90 | 73 / 459 |
| muscle | 21% | 51.63 | 168 / 803 | 0% | 0 | 0 / 0 |
| skin | 6% | 12.29 | 103 / 1809 | 9% | 0.25 | 41 / 472 |
| ovary | 4% | 7.37 | 7 / 180 | 10% | 0.43 | 45 / 430 |
| prostate | 11% | 23.02 | 26 / 245 | 4% | 0.19 | 18 / 502 |
| blood vessel | 14% | 94.46 | 187 / 1335 | 0% | 0 | 0 / 0 |
| intestine | 5% | 8.98 | 50 / 966 | 8% | 0.16 | 40 / 527 |
| brain | 2% | 4.80 | 41 / 2642 | 10% | 0.15 | 67 / 705 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 0.18 | 3 / 29 |
| liver | 4% | 4.09 | 9 / 226 | 6% | 0.12 | 24 / 406 |
| esophagus | 7% | 10.36 | 108 / 1445 | 2% | 0.04 | 3 / 183 |
| eye | 0% | 0 | 0 / 0 | 8% | 0.43 | 6 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 7% | 0.62 | 3 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0002026 | Biological process | regulation of the force of heart contraction |
| GO_0032781 | Biological process | positive regulation of ATP-dependent activity |
| GO_0060048 | Biological process | cardiac muscle contraction |
| GO_0005829 | Cellular component | cytosol |
| GO_0016460 | Cellular component | myosin II complex |
| GO_0031672 | Cellular component | A band |
| GO_0032038 | Molecular function | myosin II heavy chain binding |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0051015 | Molecular function | actin filament binding |
| GO_0003785 | Molecular function | actin monomer binding |
| Gene name | MYL4 |
| Protein name | Myosin light chain 4 Myosin light chain 4 (Myosin light chain 1, embryonic muscle/atrial isoform) (Myosin light chain alkali GT-1 isoform) |
| Synonyms | MLC1 PRO1957 |
| Description | FUNCTION: Regulatory light chain of myosin. Does not bind calcium. |
| Accessions | ENST00000354968.5 ENST00000393450.5 ENST00000572316.5 ENST00000571981.5 I3L4B1 ENST00000570671.1 I3L1K6 I3L532 ENST00000570772.5 I3L3U1 A0A1C7CYY4 ENST00000536623.6 ENST00000576874.5 I3L1R3 P12829 ENST00000572303.1 ENST00000573747.6 |
