I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| cardiac muscle cell | 6 studies | 47% ± 13% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| cardiac muscle cell | 6 studies | 47% ± 13% |
Insufficient scRNA-seq data for expression of MYH6 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| muscle | 100% | 28858.63 | 802 / 803 | 0% | 0 | 0 / 0 |
| heart | 100% | 601417.94 | 859 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 14% | 60.90 | 37 / 258 | 22% | 1.56 | 51 / 230 |
| prostate | 24% | 371.59 | 59 / 245 | 7% | 0.41 | 36 / 502 |
| ovary | 10% | 65.08 | 18 / 180 | 13% | 0.63 | 57 / 430 |
| thymus | 13% | 274.40 | 82 / 653 | 9% | 0.63 | 54 / 605 |
| lung | 14% | 755.70 | 83 / 578 | 1% | 0.03 | 12 / 1155 |
| blood vessel | 14% | 741.66 | 193 / 1335 | 0% | 0 | 0 / 0 |
| breast | 14% | 523.66 | 62 / 459 | 0% | 0.01 | 2 / 1118 |
| skin | 12% | 214.46 | 222 / 1809 | 1% | 0.01 | 3 / 472 |
| intestine | 11% | 71.53 | 109 / 966 | 1% | 0.02 | 4 / 527 |
| peripheral blood | 12% | 59.03 | 107 / 929 | 0% | 0 | 0 / 0 |
| esophagus | 11% | 69.18 | 164 / 1445 | 0% | 0 | 0 / 183 |
| adipose | 11% | 108.23 | 136 / 1204 | 0% | 0 | 0 / 0 |
| uterus | 6% | 29.32 | 11 / 170 | 5% | 0.65 | 22 / 459 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 0.34 | 3 / 29 |
| brain | 8% | 53.29 | 219 / 2642 | 0% | 0.02 | 2 / 705 |
| stomach | 7% | 41.89 | 26 / 359 | 1% | 0.01 | 2 / 286 |
| pancreas | 6% | 24.78 | 21 / 328 | 1% | 0.01 | 1 / 178 |
| tonsil | 0% | 0 | 0 / 0 | 7% | 0.17 | 3 / 45 |
| liver | 6% | 21.27 | 13 / 226 | 0% | 0.03 | 2 / 406 |
| spleen | 6% | 21.82 | 14 / 241 | 0% | 0 | 0 / 0 |
| kidney | 6% | 22.56 | 5 / 89 | 0% | 0.00 | 1 / 901 |
| bladder | 0% | 0 | 0 / 21 | 1% | 0.02 | 5 / 504 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006941 | Biological process | striated muscle contraction |
| GO_0001701 | Biological process | in utero embryonic development |
| GO_0014898 | Biological process | cardiac muscle hypertrophy in response to stress |
| GO_0055013 | Biological process | cardiac muscle cell development |
| GO_0008217 | Biological process | regulation of blood pressure |
| GO_0043462 | Biological process | regulation of ATP-dependent activity |
| GO_0002026 | Biological process | regulation of the force of heart contraction |
| GO_0002027 | Biological process | regulation of heart rate |
| GO_0006936 | Biological process | muscle contraction |
| GO_0046034 | Biological process | ATP metabolic process |
| GO_0060420 | Biological process | regulation of heart growth |
| GO_0060048 | Biological process | cardiac muscle contraction |
| GO_0055010 | Biological process | ventricular cardiac muscle tissue morphogenesis |
| GO_0007512 | Biological process | adult heart development |
| GO_0030239 | Biological process | myofibril assembly |
| GO_0007522 | Biological process | visceral muscle development |
| GO_0045214 | Biological process | sarcomere organization |
| GO_0008016 | Biological process | regulation of heart contraction |
| GO_0055009 | Biological process | atrial cardiac muscle tissue morphogenesis |
| GO_0030049 | Biological process | muscle filament sliding |
| GO_0005859 | Cellular component | muscle myosin complex |
| GO_0032982 | Cellular component | myosin filament |
| GO_0030018 | Cellular component | Z disc |
| GO_0030016 | Cellular component | myofibril |
| GO_0001725 | Cellular component | stress fiber |
| GO_0030017 | Cellular component | sarcomere |
| GO_0016460 | Cellular component | myosin II complex |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0016459 | Cellular component | myosin complex |
| GO_0017018 | Molecular function | myosin phosphatase activity |
| GO_0019901 | Molecular function | protein kinase binding |
| GO_0051015 | Molecular function | actin filament binding |
| GO_0000146 | Molecular function | microfilament motor activity |
| GO_0005524 | Molecular function | ATP binding |
| GO_0005516 | Molecular function | calmodulin binding |
| Gene name | MYH6 |
| Protein name | Myosin heavy chain 6 Myosin-6 (Myosin heavy chain 6) (Myosin heavy chain, cardiac muscle alpha isoform) (MyHC-alpha) MYH6 protein Myosin 6 |
| Synonyms | MYHCA |
| Description | FUNCTION: Muscle contraction. |
| Accessions | A0A7R6M6S1 Q1ED46 A0A1B1HY05 A0A7R6M8N5 ENST00000405093.9 A0A7R6RQK0 A0A7R6M6S3 P13533 |
