MTMR1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0060304Biological processregulation of phosphatidylinositol dephosphorylation
GO_0046856Biological processphosphatidylinositol dephosphorylation
GO_0006661Biological processphosphatidylinositol biosynthetic process
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0004438Molecular functionphosphatidylinositol-3-phosphate phosphatase activity
GO_0042803Molecular functionprotein homodimerization activity
GO_0052629Molecular functionphosphatidylinositol-3,5-bisphosphate 3-phosphatase activity

IV. Literature review

[source]
Gene nameMTMR1
Protein nameMyotubularin related protein 1
MTMR1 protein (Myotubularin related protein 1)
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase (EC 3.1.3.64) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase)
Myotubularin-related protein 1 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)
SynonymshCG_1640369
DescriptionFUNCTION: Lipid phosphatase that has high specificity for phosphatidylinositol 3-phosphate and has no activity with phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate . Activity with phosphatidylinositol (3,5)-bisphosphate is controversial; it has been shown by PubMed:27018598, while PubMed:11733541 find no activity with this substrate. .

AccessionsENST00000436701.5
F8W764
ENST00000434699.6
ENST00000438018.5
E9PPP8
F8WA39
H0YDX3
ENST00000439546.6
ENST00000445323.7
ENST00000542156.5
F8W8S8
Q13613
ENST00000493995.6
ENST00000488357.1
H7C406
H7BZJ1
E9PIH9
ENST00000490316.7
ENST00000370390.7 [Q13613-1]
ENST00000485376.5 [Q13613-2]
ENST00000429965.6
B7Z3D5
Q8NEC6