Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 27% ± 4% | |
| dendritic cell | 3 studies | 31% ± 3% |
Insufficient scRNA-seq data for expression of MRM2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 980.76 | 2640 / 2642 | 0% | 0.00 | 1 / 705 |
| adipose | 100% | 1014.39 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| adrenal gland | 100% | 1365.52 | 258 / 258 | 0% | 0 | 0 / 230 |
| bladder | 100% | 1202.48 | 21 / 21 | 0% | 0 | 0 / 504 |
| breast | 100% | 1084.26 | 459 / 459 | 0% | 0 | 0 / 1118 |
| esophagus | 100% | 1159.52 | 1445 / 1445 | 0% | 0 | 0 / 183 |
| intestine | 100% | 1161.52 | 966 / 966 | 0% | 0 | 0 / 527 |
| kidney | 100% | 1024.18 | 89 / 89 | 0% | 0 | 0 / 901 |
| liver | 100% | 819.25 | 226 / 226 | 0% | 0 | 0 / 406 |
| ovary | 100% | 1046.76 | 180 / 180 | 0% | 0 | 0 / 430 |
| prostate | 100% | 1141.56 | 245 / 245 | 0% | 0 | 0 / 502 |
| skin | 100% | 1556.71 | 1809 / 1809 | 0% | 0 | 0 / 472 |
| spleen | 100% | 1600.02 | 241 / 241 | 0% | 0 | 0 / 0 |
| stomach | 100% | 878.34 | 359 / 359 | 0% | 0 | 0 / 286 |
| thymus | 100% | 1096.13 | 653 / 653 | 0% | 0 | 0 / 605 |
| uterus | 100% | 1128.64 | 170 / 170 | 0% | 0 | 0 / 459 |
| muscle | 100% | 1159.89 | 802 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1018.35 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| pancreas | 98% | 562.11 | 323 / 328 | 0% | 0 | 0 / 178 |
| lung | 98% | 988.76 | 567 / 578 | 0% | 0.00 | 1 / 1155 |
| heart | 98% | 806.89 | 842 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 87% | 1136.25 | 807 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0001510 | Biological process | RNA methylation |
| GO_0006364 | Biological process | rRNA processing |
| GO_1902775 | Biological process | mitochondrial large ribosomal subunit assembly |
| GO_0000451 | Biological process | rRNA 2'-O-methylation |
| GO_0031167 | Biological process | rRNA methylation |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0008650 | Molecular function | rRNA (uridine-2'-O-)-methyltransferase activity |
| Gene name | MRM2 |
| Protein name | rRNA methyltransferase 2, mitochondrial rRNA methyltransferase 2, mitochondrial (EC 2.1.1.-) (16S rRNA (uridine(1369)-2'-O)-methyltransferase) (16S rRNA [Um1369] 2'-O-methyltransferase) (Protein ftsJ homolog 2) Mitochondrial rRNA methyltransferase 2 |
| Synonyms | FTSJ2 FJH1 |
| Description | FUNCTION: S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1369 (Um1369) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. . |
| Accessions | A0A3B3ITW8 ENST00000242257.14 ENST00000651235.1 ENST00000440306.3 Q1WWK4 Q9UI43 ENST00000486040.1 |