MRM2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MRM2 at tissue level.

III. Associated gene sets

GO_0001510Biological processRNA methylation
GO_0006364Biological processrRNA processing
GO_1902775Biological processmitochondrial large ribosomal subunit assembly
GO_0000451Biological processrRNA 2'-O-methylation
GO_0031167Biological processrRNA methylation
GO_0005730Cellular componentnucleolus
GO_0005759Cellular componentmitochondrial matrix
GO_0005739Cellular componentmitochondrion
GO_0008650Molecular functionrRNA (uridine-2'-O-)-methyltransferase activity

IV. Literature review

[source]
Gene nameMRM2
Protein namerRNA methyltransferase 2, mitochondrial
rRNA methyltransferase 2, mitochondrial (EC 2.1.1.-) (16S rRNA (uridine(1369)-2'-O)-methyltransferase) (16S rRNA [Um1369] 2'-O-methyltransferase) (Protein ftsJ homolog 2)
Mitochondrial rRNA methyltransferase 2
SynonymsFTSJ2
FJH1
DescriptionFUNCTION: S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1369 (Um1369) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. .

AccessionsA0A3B3ITW8
ENST00000242257.14
ENST00000651235.1
ENST00000440306.3
Q1WWK4
Q9UI43
ENST00000486040.1