MOGAT3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MOGAT3 at tissue level.

III. Associated gene sets

GO_0006071Biological processglycerol metabolic process
GO_0019432Biological processtriglyceride biosynthetic process
GO_0006640Biological processmonoacylglycerol biosynthetic process
GO_1990578Cellular componentperinuclear endoplasmic reticulum membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0003846Molecular function2-acylglycerol O-acyltransferase activity
GO_0004144Molecular functiondiacylglycerol O-acyltransferase activity

IV. Literature review

[source]
Gene nameMOGAT3
Protein name2-acylglycerol O-acyltransferase 3 (EC 2.3.1.20) (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 3) (MGAT3) (Diacylglycerol O-acyltransferase candidate 7) (hDC7) (Diacylglycerol acyltransferase 2-like protein 7) (Monoacylglycerol O-acyltransferase 3)
SynonymsDC7
DGAT2L7
UNQ9383/PRO34208
DescriptionFUNCTION: Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Also able to catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl-CoA as substrates. Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. Also able to use 1-monoalkylglycerol (1-MAkG) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG) . .

AccessionsENST00000379423.3 [Q86VF5-2]
ENST00000440203.6 [Q86VF5-3]
ENST00000223114.9 [Q86VF5-1]
Q86VF5