MMP21 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MMP21 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MMP21 at tissue level.

III. Associated gene sets

GO_0002244Biological processhematopoietic progenitor cell differentiation
GO_0030198Biological processextracellular matrix organization
GO_0060976Biological processcoronary vasculature development
GO_0030574Biological processcollagen catabolic process
GO_0061371Biological processdetermination of heart left/right asymmetry
GO_0006508Biological processproteolysis
GO_0007368Biological processdetermination of left/right symmetry
GO_0005576Cellular componentextracellular region
GO_0031012Cellular componentextracellular matrix
GO_0004222Molecular functionmetalloendopeptidase activity
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameMMP21
Protein nameMatrix metalloproteinase-21 (MMP-21) (EC 3.4.24.-)
Matrix metallopeptidase 21
Synonyms
DescriptionFUNCTION: Plays a specialized role in the generation of left-right asymmetry during embryogenesis. May act as a negative regulator of the NOTCH-signaling pathway . Cleaves alpha-1-antitrypsin . .

AccessionsA0A494C1E5
A0A494C1J6
ENST00000651977.1
ENST00000651834.1
A0A494C0E5
Q8N119
ENST00000652044.1
ENST00000368808.3