MMP17 | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte precursor cell	6 studies	26% ± 5%	Explore
glutamatergic neuron	5 studies	33% ± 23%	Explore
neuron	3 studies	21% ± 1%	Explore
endothelial cell	3 studies	26% ± 7%	Explore

Name	Number of supported studies	Average coverage
brain	3 studies	31% ± 19%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	97%	660.77	1750 / 1809	98%	80.05	462 / 472
brain	96%	2556.20	2525 / 2642	93%	14.65	656 / 705
breast	94%	559.17	432 / 459	78%	7.12	872 / 1118
uterus	78%	510.69	133 / 170	58%	5.17	266 / 459
lung	70%	251.58	405 / 578	63%	4.73	731 / 1155
bladder	76%	331.62	16 / 21	49%	2.89	247 / 504
esophagus	64%	361.72	920 / 1445	56%	3.76	102 / 183
ovary	99%	1613.97	179 / 180	19%	1.57	81 / 430
intestine	80%	601.61	770 / 966	37%	2.09	195 / 527
eye	0%	0	0 / 0	100%	68.27	80 / 80
prostate	83%	407.34	204 / 245	15%	0.45	77 / 502
pancreas	23%	99.79	76 / 328	74%	4.14	131 / 178
adipose	89%	506.18	1077 / 1204	0%	0	0 / 0
thymus	62%	214.83	407 / 653	26%	1.54	156 / 605
adrenal gland	11%	42.46	28 / 258	61%	8.54	141 / 230
peripheral blood	71%	334.86	662 / 929	0%	0	0 / 0
stomach	31%	148.14	110 / 359	36%	2.19	103 / 286
spleen	61%	215.04	148 / 241	0%	0	0 / 0
lymph node	0%	0	0 / 0	52%	2.48	15 / 29
tonsil	0%	0	0 / 0	47%	2.19	21 / 45
kidney	16%	49.99	14 / 89	17%	0.96	150 / 901
heart	29%	97.93	253 / 861	0%	0	0 / 0
liver	7%	24.73	16 / 226	19%	1.23	77 / 406
blood vessel	19%	69.35	253 / 1335	0%	0	0 / 0
muscle	6%	19.60	52 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0042756	Biological process	drinking behavior
GO_0030198	Biological process	extracellular matrix organization
GO_0001822	Biological process	kidney development
GO_0030574	Biological process	collagen catabolic process
GO_0006508	Biological process	proteolysis
GO_0005615	Cellular component	extracellular space
GO_0098552	Cellular component	side of membrane
GO_0005886	Cellular component	plasma membrane
GO_0031012	Cellular component	extracellular matrix
GO_0004222	Molecular function	metalloendopeptidase activity
GO_0008047	Molecular function	enzyme activator activity
GO_0070006	Molecular function	metalloaminopeptidase activity
GO_0008270	Molecular function	zinc ion binding

Gene name	MMP17
Protein name	Matrix metalloproteinase-17 (MMP-17) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (MTMMP4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP) (MT4MMP) Matrix metallopeptidase 17 MMP17 protein
Synonyms	MT4MMP
Description	FUNCTION: Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-\|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.
Accessions	ENST00000545790.6 ENST00000535291.5 [Q9ULZ9-2] F5GWR3 ENST00000360564.5 [Q9ULZ9-1] F5GZA7 ENST00000535004.2 F5H209 ENST00000545671.6 Q5U5M0 Q8IWC3 Q9ULZ9

MMP17 report