I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| fibroblast | 3 studies | 25% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| fibroblast | 3 studies | 25% ± 7% |
Insufficient scRNA-seq data for expression of MMP11 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 97% | 301.74 | 443 / 459 | 88% | 321.43 | 988 / 1118 |
| uterus | 100% | 4999.41 | 170 / 170 | 71% | 162.52 | 328 / 459 |
| intestine | 100% | 543.28 | 964 / 966 | 68% | 118.67 | 358 / 527 |
| bladder | 100% | 306.19 | 21 / 21 | 58% | 137.75 | 290 / 504 |
| ovary | 100% | 1565.80 | 180 / 180 | 51% | 131.76 | 221 / 430 |
| esophagus | 85% | 251.06 | 1232 / 1445 | 58% | 110.05 | 107 / 183 |
| stomach | 79% | 173.52 | 282 / 359 | 62% | 98.39 | 178 / 286 |
| pancreas | 49% | 100.58 | 160 / 328 | 87% | 532.52 | 155 / 178 |
| lung | 58% | 100.78 | 337 / 578 | 57% | 102.40 | 663 / 1155 |
| kidney | 93% | 320.33 | 83 / 89 | 12% | 7.50 | 111 / 901 |
| skin | 85% | 373.36 | 1545 / 1809 | 19% | 21.19 | 90 / 472 |
| spleen | 100% | 216.27 | 240 / 241 | 0% | 0 | 0 / 0 |
| prostate | 96% | 278.24 | 236 / 245 | 2% | 3.37 | 12 / 502 |
| blood vessel | 97% | 437.08 | 1296 / 1335 | 0% | 0 | 0 / 0 |
| heart | 97% | 536.84 | 834 / 861 | 0% | 0 | 0 / 0 |
| adipose | 94% | 365.26 | 1129 / 1204 | 0% | 0 | 0 / 0 |
| thymus | 85% | 187.31 | 556 / 653 | 8% | 7.33 | 51 / 605 |
| adrenal gland | 86% | 207.91 | 222 / 258 | 3% | 2.98 | 8 / 230 |
| tonsil | 0% | 0 | 0 / 0 | 44% | 93.63 | 20 / 45 |
| muscle | 43% | 52.52 | 344 / 803 | 0% | 0 | 0 / 0 |
| liver | 18% | 28.05 | 40 / 226 | 16% | 17.86 | 64 / 406 |
| brain | 31% | 40.94 | 827 / 2642 | 1% | 0.77 | 7 / 705 |
| peripheral blood | 11% | 12.03 | 98 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 2.55 | 1 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0071711 | Biological process | basement membrane organization |
| GO_0030198 | Biological process | extracellular matrix organization |
| GO_0022617 | Biological process | extracellular matrix disassembly |
| GO_0030199 | Biological process | collagen fibril organization |
| GO_0045599 | Biological process | negative regulation of fat cell differentiation |
| GO_0030574 | Biological process | collagen catabolic process |
| GO_0006508 | Biological process | proteolysis |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005796 | Cellular component | Golgi lumen |
| GO_0005576 | Cellular component | extracellular region |
| GO_0031012 | Cellular component | extracellular matrix |
| GO_0004222 | Molecular function | metalloendopeptidase activity |
| GO_0004252 | Molecular function | serine-type endopeptidase activity |
| GO_0008270 | Molecular function | zinc ion binding |
| Gene name | MMP11 |
| Protein name | Stromelysin-3 (SL-3) (ST3) (EC 3.4.24.-) (Matrix metalloproteinase-11) (MMP-11) Matrix metallopeptidase 11 (Stromelysin 3), isoform CRA_b (cDNA PSEC0140 fis, clone PLACE1005783, highly similar to STROMELYSIN-3) Matrix metallopeptidase 11 (Stromelysin-3) Matrix metalloproteinase 11 |
| Synonyms | STMY3 hCG_41094 |
| Description | FUNCTION: May play an important role in the progression of epithelial malignancies. |
| Accessions | P24347 ENST00000215743.8 ENST00000437086.5 ENST00000627283.1 ENST00000434318.1 ENST00000629514.2 A5GZ71 B3KQS8 E9PED7 H7C3I7 ENST00000612388.3 |
