I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| basal cell | 6 studies | 33% ± 14% | |
| respiratory goblet cell | 4 studies | 24% ± 2% | |
| secretory cell | 3 studies | 17% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| basal cell | 6 studies | 33% ± 14% | |
| respiratory goblet cell | 4 studies | 24% ± 2% | |
| secretory cell | 3 studies | 17% ± 1% |
Insufficient scRNA-seq data for expression of MMP10 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 56% | 119.94 | 137 / 245 | 67% | 14.53 | 337 / 502 |
| lung | 65% | 149.53 | 373 / 578 | 54% | 122.94 | 622 / 1155 |
| stomach | 68% | 157.24 | 243 / 359 | 41% | 7.02 | 118 / 286 |
| uterus | 54% | 94.59 | 91 / 170 | 53% | 128.93 | 244 / 459 |
| pancreas | 34% | 12.37 | 112 / 328 | 62% | 15.54 | 110 / 178 |
| intestine | 39% | 25.05 | 380 / 966 | 42% | 7.64 | 223 / 527 |
| esophagus | 10% | 8.23 | 148 / 1445 | 66% | 55.91 | 120 / 183 |
| bladder | 24% | 50.05 | 5 / 21 | 46% | 36.14 | 233 / 504 |
| breast | 31% | 9.65 | 143 / 459 | 34% | 10.93 | 384 / 1118 |
| tonsil | 0% | 0 | 0 / 0 | 62% | 39.47 | 28 / 45 |
| ovary | 12% | 18.51 | 22 / 180 | 23% | 21.88 | 99 / 430 |
| skin | 27% | 10.14 | 480 / 1809 | 8% | 2.92 | 36 / 472 |
| spleen | 23% | 6.10 | 55 / 241 | 0% | 0 | 0 / 0 |
| kidney | 21% | 4.64 | 19 / 89 | 1% | 0.72 | 8 / 901 |
| liver | 14% | 81.36 | 31 / 226 | 8% | 3.15 | 34 / 406 |
| adipose | 16% | 5.52 | 195 / 1204 | 0% | 0 | 0 / 0 |
| thymus | 12% | 4.02 | 80 / 653 | 3% | 1.90 | 21 / 605 |
| blood vessel | 9% | 3.18 | 117 / 1335 | 0% | 0 | 0 / 0 |
| adrenal gland | 7% | 2.70 | 18 / 258 | 2% | 0.16 | 4 / 230 |
| brain | 7% | 2.05 | 176 / 2642 | 1% | 0.11 | 5 / 705 |
| heart | 5% | 1.30 | 42 / 861 | 0% | 0 | 0 / 0 |
| muscle | 3% | 0.46 | 28 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 3% | 6.19 | 32 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0030198 | Biological process | extracellular matrix organization |
| GO_0022617 | Biological process | extracellular matrix disassembly |
| GO_0030574 | Biological process | collagen catabolic process |
| GO_0006508 | Biological process | proteolysis |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0031012 | Cellular component | extracellular matrix |
| GO_0004222 | Molecular function | metalloendopeptidase activity |
| GO_0004252 | Molecular function | serine-type endopeptidase activity |
| GO_0008270 | Molecular function | zinc ion binding |
| Gene name | MMP10 |
| Protein name | Matrix metallopeptidase 10 Stromelysin-2 (SL-2) (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) |
| Synonyms | STMY2 |
| Description | FUNCTION: Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase. |
| Accessions | P09238 ENST00000279441.9 F5GYX7 ENST00000539681.1 |
