METTL25 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
oligodendrocyte	8 studies	27% ± 9%	Explore
astrocyte	7 studies	37% ± 16%	Explore
adipocyte	6 studies	22% ± 3%	Explore
oligodendrocyte precursor cell	6 studies	30% ± 11%	Explore
microglial cell	5 studies	20% ± 5%	Explore
endothelial cell	4 studies	25% ± 7%	Explore
cardiac muscle cell	4 studies	18% ± 2%	Explore
GABAergic neuron	4 studies	42% ± 15%	Explore
glutamatergic neuron	4 studies	53% ± 20%	Explore
interneuron	3 studies	41% ± 19%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	5 studies	45% ± 15%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	371.58	459 / 459	100%	6.00	1115 / 1118
thymus	100%	440.95	653 / 653	100%	6.29	603 / 605
prostate	100%	344.39	245 / 245	100%	5.95	500 / 502
ovary	100%	354.17	180 / 180	100%	3.40	428 / 430
kidney	100%	307.15	89 / 89	99%	4.78	894 / 901
adrenal gland	100%	322.64	258 / 258	99%	3.61	228 / 230
bladder	100%	318.10	21 / 21	99%	3.91	499 / 504
uterus	100%	324.52	170 / 170	99%	4.22	454 / 459
esophagus	100%	268.71	1445 / 1445	98%	2.80	180 / 183
intestine	100%	323.29	966 / 966	98%	3.49	518 / 527
lung	99%	249.38	570 / 578	100%	4.13	1151 / 1155
brain	98%	164.64	2600 / 2642	100%	3.37	704 / 705
stomach	100%	209.44	359 / 359	98%	3.38	280 / 286
pancreas	98%	140.96	322 / 328	98%	3.79	175 / 178
liver	100%	150.22	225 / 226	94%	2.36	383 / 406
skin	100%	328.93	1809 / 1809	92%	3.12	435 / 472
spleen	100%	340.90	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	3.96	45 / 45
ureter	0%	0	0 / 0	100%	1.82	1 / 1
adipose	100%	327.57	1203 / 1204	0%	0	0 / 0
blood vessel	100%	362.31	1333 / 1335	0%	0	0 / 0
muscle	100%	248.26	801 / 803	0%	0	0 / 0
heart	97%	185.31	833 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	4.13	28 / 29
eye	0%	0	0 / 0	90%	2.89	72 / 80
peripheral blood	89%	189.03	825 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0