Insufficient scRNA-seq data for expression of MEIOC at single-cell level.
Insufficient scRNA-seq data for expression of MEIOC at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
uterus | 98% | 32.84 | 167 / 170 | 12% | 0.24 | 54 / 459 |
skin | 98% | 52.45 | 1772 / 1809 | 3% | 0.04 | 15 / 472 |
brain | 98% | 88.69 | 2582 / 2642 | 3% | 0.03 | 19 / 705 |
ovary | 90% | 25.10 | 162 / 180 | 10% | 0.18 | 41 / 430 |
muscle | 100% | 70.38 | 799 / 803 | 0% | 0 | 0 / 0 |
kidney | 98% | 33.35 | 87 / 89 | 1% | 0.02 | 10 / 901 |
bladder | 95% | 25.71 | 20 / 21 | 2% | 0.04 | 11 / 504 |
breast | 92% | 31.73 | 423 / 459 | 5% | 0.11 | 51 / 1118 |
esophagus | 90% | 22.63 | 1296 / 1445 | 7% | 0.17 | 12 / 183 |
intestine | 94% | 28.29 | 910 / 966 | 2% | 0.03 | 9 / 527 |
thymus | 94% | 27.17 | 614 / 653 | 0% | 0 | 0 / 605 |
prostate | 93% | 27.96 | 228 / 245 | 0% | 0.00 | 1 / 502 |
lung | 84% | 22.23 | 485 / 578 | 9% | 0.32 | 105 / 1155 |
liver | 92% | 25.49 | 209 / 226 | 0% | 0 | 0 / 406 |
spleen | 92% | 23.55 | 222 / 241 | 0% | 0 | 0 / 0 |
adipose | 90% | 23.84 | 1078 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 87% | 23.40 | 1166 / 1335 | 0% | 0 | 0 / 0 |
stomach | 78% | 17.91 | 280 / 359 | 2% | 0.06 | 7 / 286 |
adrenal gland | 79% | 16.87 | 203 / 258 | 0% | 0.00 | 1 / 230 |
heart | 76% | 16.95 | 657 / 861 | 0% | 0 | 0 / 0 |
pancreas | 57% | 9.30 | 186 / 328 | 1% | 0.01 | 1 / 178 |
peripheral blood | 28% | 8.22 | 264 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 16% | 0.48 | 7 / 45 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0048599 | Biological process | oocyte development |
GO_0007144 | Biological process | female meiosis I |
GO_0051310 | Biological process | metaphase chromosome alignment |
GO_0007130 | Biological process | synaptonemal complex assembly |
GO_0048255 | Biological process | mRNA stabilization |
GO_0070192 | Biological process | chromosome organization involved in meiotic cell cycle |
GO_0007286 | Biological process | spermatid development |
GO_0051729 | Biological process | germline cell cycle switching, mitotic to meiotic cell cycle |
GO_0007141 | Biological process | male meiosis I |
GO_0006302 | Biological process | double-strand break repair |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
Gene name | MEIOC |
Protein name | Meiosis-specific coiled-coil domain-containing protein MEIOC (Meiosis-specific with coiled-coil domain protein) Meiosis specific with coiled-coil domain |
Synonyms | C17orf104 |
Description | FUNCTION: Is required for meiosis completion in both male and female germ cells. Confers stability to numerous meiotic mRNAs in gonads allowing proper initiation and progression into meiosis prophase I. The function may involve YTHDC2 and is independent of induction by retinoic acid (RA). Maintains an extended meiotic prophase I by properly promoting the transition from a mitotic to a meiotic cell cycle program by binding transcripts through its interaction with YTHDC2 that regulate the mitotic cell cycle. . |
Accessions | C9JC06 K7EPA7 ENST00000425535.5 ENST00000409122.7 [A2RUB1-4] ENST00000432494.1 ENST00000472403.5 C9JYK8 ENST00000456912.1 A2RUB1 ENST00000409464.1 [A2RUB1-1] C9J4A2 |