MDGA1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MDGA1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MDGA1 at tissue level.

III. Associated gene sets

GO_0007420Biological processbrain development
GO_0099179Biological processregulation of synaptic membrane adhesion
GO_0001764Biological processneuron migration
GO_0021527Biological processspinal cord association neuron differentiation
GO_1905606Biological processregulation of presynapse assembly
GO_0007399Biological processnervous system development
GO_0021799Biological processcerebral cortex radially oriented cell migration
GO_0098982Cellular componentGABA-ergic synapse
GO_0005615Cellular componentextracellular space
GO_0098552Cellular componentside of membrane
GO_0005576Cellular componentextracellular region
GO_0005794Cellular componentGolgi apparatus
GO_0005886Cellular componentplasma membrane
GO_0003674Molecular functionmolecular_function

IV. Literature review

[source]
Gene nameMDGA1
Protein nameAlternative protein MDGA1
MAM domain containing glycosylphosphatidylinositol anchor 1
MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3)
SynonymsMAMDC3
DescriptionFUNCTION: Required for radial migration of cortical neurons in the superficial layer of the neocortex (By similarity). Plays a role in the formation or maintenance of inhibitory synapses. May function by inhibiting the activity of NLGN2. .

AccessionsENST00000650466.1
Q8NFP4
ENST00000505425.5 [Q8NFP4-2]
ENST00000508399.1
H0YA23
H0Y4Q2
L8EAS0
ENST00000680397.1
ENST00000681439.1
A0A7P0TB62
D6RHU8
ENST00000515437.5
A0A7P0TB21
A0A3B3IU48
D6RFG6
A0A7P0T822
ENST00000418178.2
ENST00000502298.1
ENST00000434837.8 [Q8NFP4-1]
ENST00000681472.1