Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 20 studies | 49% ± 18% | |
oligodendrocyte | 13 studies | 46% ± 14% | |
oligodendrocyte precursor cell | 12 studies | 41% ± 17% | |
endothelial cell | 11 studies | 31% ± 17% | |
glutamatergic neuron | 11 studies | 46% ± 22% | |
GABAergic neuron | 9 studies | 51% ± 18% | |
epithelial cell | 7 studies | 30% ± 11% | |
goblet cell | 6 studies | 41% ± 21% | |
interneuron | 6 studies | 54% ± 22% | |
ciliated cell | 6 studies | 24% ± 6% | |
retina horizontal cell | 6 studies | 45% ± 18% | |
Mueller cell | 6 studies | 32% ± 10% | |
neuron | 5 studies | 45% ± 14% | |
club cell | 5 studies | 26% ± 12% | |
capillary endothelial cell | 5 studies | 27% ± 7% | |
respiratory goblet cell | 4 studies | 22% ± 5% | |
squamous epithelial cell | 4 studies | 43% ± 21% | |
pericyte | 4 studies | 33% ± 17% | |
fibroblast | 4 studies | 29% ± 4% | |
secretory cell | 3 studies | 23% ± 6% | |
GABAergic interneuron | 3 studies | 50% ± 15% | |
glial cell | 3 studies | 33% ± 11% | |
granule cell | 3 studies | 35% ± 10% | |
basal cell | 3 studies | 28% ± 7% | |
GABAergic amacrine cell | 3 studies | 25% ± 7% | |
amacrine cell | 3 studies | 24% ± 9% | |
glycinergic amacrine cell | 3 studies | 24% ± 5% | |
ependymal cell | 3 studies | 37% ± 21% | |
enteroendocrine cell | 3 studies | 25% ± 2% | |
chondrocyte | 3 studies | 25% ± 3% | |
type I pneumocyte | 3 studies | 20% ± 5% | |
erythrocyte | 3 studies | 36% ± 12% | |
erythroblast | 3 studies | 39% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 4021.34 | 2642 / 2642 | 100% | 49.63 | 703 / 705 |
prostate | 100% | 2413.48 | 244 / 245 | 100% | 85.29 | 500 / 502 |
esophagus | 100% | 3979.29 | 1444 / 1445 | 95% | 37.07 | 173 / 183 |
lung | 100% | 3070.44 | 577 / 578 | 92% | 23.78 | 1060 / 1155 |
uterus | 99% | 2009.74 | 169 / 170 | 91% | 25.22 | 417 / 459 |
breast | 88% | 1349.27 | 402 / 459 | 98% | 40.55 | 1099 / 1118 |
thymus | 99% | 1718.60 | 648 / 653 | 85% | 21.32 | 515 / 605 |
intestine | 100% | 2360.37 | 964 / 966 | 84% | 17.64 | 441 / 527 |
bladder | 100% | 1634.76 | 21 / 21 | 81% | 18.21 | 408 / 504 |
ovary | 100% | 2122.99 | 180 / 180 | 80% | 12.25 | 346 / 430 |
skin | 100% | 4454.45 | 1807 / 1809 | 79% | 12.72 | 372 / 472 |
stomach | 90% | 1262.25 | 324 / 359 | 79% | 15.17 | 226 / 286 |
kidney | 100% | 1880.96 | 89 / 89 | 53% | 6.67 | 479 / 901 |
ureter | 0% | 0 | 0 / 0 | 100% | 20.19 | 1 / 1 |
pancreas | 3% | 21.84 | 9 / 328 | 95% | 28.12 | 169 / 178 |
blood vessel | 97% | 1366.55 | 1292 / 1335 | 0% | 0 | 0 / 0 |
spleen | 95% | 1224.99 | 230 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 91% | 25.04 | 41 / 45 |
peripheral blood | 85% | 2459.49 | 792 / 929 | 0% | 0 | 0 / 0 |
adipose | 80% | 877.80 | 958 / 1204 | 0% | 0 | 0 / 0 |
heart | 77% | 856.84 | 664 / 861 | 0% | 0 | 0 / 0 |
adrenal gland | 5% | 52.79 | 14 / 258 | 62% | 10.27 | 142 / 230 |
eye | 0% | 0 | 0 / 0 | 39% | 3.74 | 31 / 80 |
muscle | 14% | 152.93 | 114 / 803 | 0% | 0 | 0 / 0 |
liver | 0% | 2.60 | 1 / 226 | 8% | 1.08 | 33 / 406 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.22 | 1 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0008654 | Biological process | phospholipid biosynthetic process |
GO_0036150 | Biological process | phosphatidylserine acyl-chain remodeling |
GO_0036151 | Biological process | phosphatidylcholine acyl-chain remodeling |
GO_0030258 | Biological process | lipid modification |
GO_0032330 | Biological process | regulation of chondrocyte differentiation |
GO_0036152 | Biological process | phosphatidylethanolamine acyl-chain remodeling |
GO_0016020 | Cellular component | membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0047144 | Molecular function | 2-acylglycerol-3-phosphate O-acyltransferase activity |
GO_0003841 | Molecular function | 1-acylglycerol-3-phosphate O-acyltransferase activity |
GO_0016746 | Molecular function | acyltransferase activity |
GO_0106263 | Molecular function | 1-acylglycerophosphoserine O-acyltransferase activity |
GO_0047184 | Molecular function | 1-acylglycerophosphocholine O-acyltransferase activity |
GO_0106262 | Molecular function | 1-acylglycerophosphoethanolamine O-acyltransferase activity |
Gene name | MBOAT2 |
Protein name | Lysophospholipid acyltransferase 2 (LPLAT 2) (EC 2.3.1.-) (1-acylglycerophosphate O-acyltransferase MBOAT2) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase MBOAT2) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine MBOAT2 O-acyltransferase) (EC 2.3.1.n7) (Lysophosphatidic acid acyltransferase) (LPAAT) (Lyso-PA acyltransferase) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 4) (Lyso-PC acyltransferase 4) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 2) (O-acyltransferase domain-containing protein 2) Membrane bound O-acyltransferase domain containing 2 |
Synonyms | OACT2 LPCAT4 |
Description | FUNCTION: Acyltransferase which catalyzes the transfer of an acyl group from an acyl-CoA to a lysophospholipid leading to the production of a phospholipid and participates in the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle . Catalyzes preferentially the acylation of lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) and lysophosphatidic acid (LPA) and to a lesser extend lysophosphatidylcholine (LPC) and lysophosphatidylserine (LPS) . Prefers oleoyl-CoA as the acyl donor . May be involved in chondrocyte differentiation (By similarity). . |
Accessions | C9J2H7 ENST00000477073.5 Q6ZWT7 F8WDJ6 ENST00000305997.8 ENST00000462696.1 H7C5D1 ENST00000471753.5 |