MBOAT2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008654Biological processphospholipid biosynthetic process
GO_0036150Biological processphosphatidylserine acyl-chain remodeling
GO_0036151Biological processphosphatidylcholine acyl-chain remodeling
GO_0030258Biological processlipid modification
GO_0032330Biological processregulation of chondrocyte differentiation
GO_0036152Biological processphosphatidylethanolamine acyl-chain remodeling
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0047144Molecular function2-acylglycerol-3-phosphate O-acyltransferase activity
GO_0003841Molecular function1-acylglycerol-3-phosphate O-acyltransferase activity
GO_0016746Molecular functionacyltransferase activity
GO_0106263Molecular function1-acylglycerophosphoserine O-acyltransferase activity
GO_0047184Molecular function1-acylglycerophosphocholine O-acyltransferase activity
GO_0106262Molecular function1-acylglycerophosphoethanolamine O-acyltransferase activity

IV. Literature review

[source]
Gene nameMBOAT2
Protein nameLysophospholipid acyltransferase 2 (LPLAT 2) (EC 2.3.1.-) (1-acylglycerophosphate O-acyltransferase MBOAT2) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase MBOAT2) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine MBOAT2 O-acyltransferase) (EC 2.3.1.n7) (Lysophosphatidic acid acyltransferase) (LPAAT) (Lyso-PA acyltransferase) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 4) (Lyso-PC acyltransferase 4) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 2) (O-acyltransferase domain-containing protein 2)
Membrane bound O-acyltransferase domain containing 2
SynonymsOACT2
LPCAT4
DescriptionFUNCTION: Acyltransferase which catalyzes the transfer of an acyl group from an acyl-CoA to a lysophospholipid leading to the production of a phospholipid and participates in the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle . Catalyzes preferentially the acylation of lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) and lysophosphatidic acid (LPA) and to a lesser extend lysophosphatidylcholine (LPC) and lysophosphatidylserine (LPS) . Prefers oleoyl-CoA as the acyl donor . May be involved in chondrocyte differentiation (By similarity). .

AccessionsC9J2H7
ENST00000477073.5
Q6ZWT7
F8WDJ6
ENST00000305997.8
ENST00000462696.1
H7C5D1
ENST00000471753.5