I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 5 studies | 48% ± 19% | |
| glutamatergic neuron | 4 studies | 47% ± 19% | |
| retinal ganglion cell | 4 studies | 36% ± 15% | |
| interneuron | 4 studies | 41% ± 15% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 5 studies | 48% ± 19% | |
| glutamatergic neuron | 4 studies | 47% ± 19% | |
| retinal ganglion cell | 4 studies | 36% ± 15% | |
| interneuron | 4 studies | 41% ± 15% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 42% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 86% | 140.76 | 2276 / 2642 | 36% | 1.21 | 257 / 705 |
| adrenal gland | 9% | 6.81 | 22 / 258 | 73% | 13.89 | 168 / 230 |
| heart | 58% | 54.92 | 499 / 861 | 0% | 0 | 0 / 0 |
| pancreas | 33% | 17.96 | 108 / 328 | 3% | 0.29 | 6 / 178 |
| prostate | 5% | 4.97 | 12 / 245 | 29% | 1.05 | 146 / 502 |
| breast | 13% | 11.95 | 59 / 459 | 14% | 0.98 | 153 / 1118 |
| thymus | 1% | 0.91 | 7 / 653 | 20% | 0.46 | 124 / 605 |
| ovary | 8% | 3.76 | 14 / 180 | 13% | 0.57 | 56 / 430 |
| kidney | 6% | 2.18 | 5 / 89 | 6% | 0.39 | 57 / 901 |
| lung | 0% | 0.17 | 1 / 578 | 7% | 0.54 | 77 / 1155 |
| uterus | 0% | 0 | 0 / 170 | 6% | 0.30 | 26 / 459 |
| skin | 1% | 0.84 | 25 / 1809 | 2% | 0.22 | 9 / 472 |
| esophagus | 0% | 0.44 | 3 / 1445 | 3% | 0.15 | 5 / 183 |
| bladder | 0% | 0 | 0 / 21 | 3% | 0.11 | 13 / 504 |
| intestine | 1% | 0.30 | 7 / 966 | 1% | 0.03 | 6 / 527 |
| stomach | 1% | 0.28 | 3 / 359 | 1% | 0.05 | 2 / 286 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.03 | 1 / 80 |
| liver | 0% | 0.43 | 1 / 226 | 1% | 0.03 | 3 / 406 |
| muscle | 0% | 0.47 | 2 / 803 | 0% | 0 | 0 / 0 |
| adipose | 0% | 0.09 | 2 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0.16 | 2 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0016567 | Biological process | protein ubiquitination |
| GO_0030659 | Cellular component | cytoplasmic vesicle membrane |
| GO_0008270 | Molecular function | zinc ion binding |
| GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
| Gene name | MARCHF11 |
| Protein name | Membrane associated ring-CH-type finger 11 E3 ubiquitin-protein ligase MARCHF11 (EC 2.3.2.27) (Membrane-associated RING finger protein 11) (Membrane-associated RING-CH protein XI) (MARCH-XI) (RING-type E3 ubiquitin transferase MARCHF11) |
| Synonyms | MARCH11 |
| Description | FUNCTION: E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids. . |
| Accessions | ENST00000507111.1 H0Y9K6 A6NNE9 ENST00000332432.9 [A6NNE9-1] |
