MAN2A2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006517Biological processprotein deglycosylation
GO_0006486Biological processprotein glycosylation
GO_0006491Biological processN-glycan processing
GO_0006013Biological processmannose metabolic process
GO_0000139Cellular componentGolgi membrane
GO_0004572Molecular functionmannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity
GO_0016799Molecular functionhydrolase activity, hydrolyzing N-glycosyl compounds
GO_0004559Molecular functionalpha-mannosidase activity
GO_0030246Molecular functioncarbohydrate binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameMAN2A2
Protein nameAlpha-mannosidase (EC 3.2.1.-)
Mannosidase alpha class 2A member 2
Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)
Mannosidase alpha class 2A member 2 (Mannosidase, alpha, class 2A, member 2, isoform CRA_f)
SynonymshCG_32578
MANA2X
DescriptionFUNCTION: Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.

AccessionsP49641
ENST00000558171.1
H0YK77
H0YKT0
H0YNG5
ENST00000559999.5
H0YLU3
ENST00000558161.5
ENST00000360468.7 [P49641-3]
ENST00000558290.5
A0A0C4DGL1
H0YKQ2
H0YMU0
ENST00000559704.1
H0YL67
ENST00000559717.6 [P49641-3]
H0YML7
H0YNC8
ENST00000560147.5
ENST00000560616.5
ENST00000557865.5
H0YLB9
ENST00000561448.5
ENST00000560451.5
ENST00000559132.3
ENST00000559965.5
H0YKH9
H0YLL4
ENST00000558853.5
ENST00000557990.1
H0YKM7