LYPD8 | OmnibusX

Name	Number of supported studies	Average coverage
goblet cell	3 studies	26% ± 3%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of LYPD8 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	69%	3282.18	669 / 966	67%	43.14	351 / 527
kidney	79%	33.97	70 / 89	0%	0.01	2 / 901
brain	61%	98.65	1599 / 2642	2%	0.06	11 / 705
stomach	1%	0.39	4 / 359	48%	33.99	137 / 286
spleen	23%	5.53	55 / 241	0%	0	0 / 0
bladder	0%	0	0 / 21	21%	10.10	105 / 504
esophagus	1%	0.74	11 / 1445	13%	4.85	23 / 183
peripheral blood	8%	1.68	76 / 929	0%	0	0 / 0
skin	3%	0.95	51 / 1809	2%	0.12	9 / 472
lung	0%	0.07	2 / 578	4%	0.95	44 / 1155
pancreas	0%	0.06	1 / 328	3%	0.23	5 / 178
uterus	2%	0.70	3 / 170	1%	0.69	6 / 459
breast	3%	27.63	14 / 459	0%	0	0 / 1118
adrenal gland	2%	0.44	4 / 258	1%	0.02	2 / 230
prostate	2%	1.38	5 / 245	0%	0	0 / 502
liver	1%	0.17	2 / 226	1%	0.04	4 / 406
blood vessel	1%	0.25	15 / 1335	0%	0	0 / 0
adipose	1%	0.36	10 / 1204	0%	0	0 / 0
thymus	0%	0.04	1 / 653	0%	0.00	1 / 605
muscle	0%	0.06	2 / 803	0%	0	0 / 0
ovary	0%	0	0 / 180	0%	0.04	1 / 430
heart	0%	0.05	2 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

Gene name	LYPD8
Protein name	Ly6/PLAUR domain-containing protein 8
Synonyms	UNQ511/PRO1026
Description	FUNCTION: Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis. .
Accessions	ENST00000590317.4 Q6UX82

GO_0050829	Biological process	defense response to Gram-negative bacterium
GO_0005615	Cellular component	extracellular space
GO_0098552	Cellular component	side of membrane
GO_0005576	Cellular component	extracellular region
GO_0005886	Cellular component	plasma membrane

LYPD8 report