Insufficient scRNA-seq data for expression of LVRN at tissue level.
Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adipose | 100% | 2080.00 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| breast | 87% | 1247.42 | 399 / 459 | 8% | 0.15 | 91 / 1118 |
| ovary | 93% | 274.84 | 168 / 180 | 1% | 0.03 | 6 / 430 |
| esophagus | 75% | 267.26 | 1086 / 1445 | 7% | 0.24 | 13 / 183 |
| intestine | 75% | 295.57 | 727 / 966 | 2% | 0.03 | 9 / 527 |
| skin | 75% | 266.12 | 1352 / 1809 | 1% | 0.79 | 5 / 472 |
| blood vessel | 75% | 180.70 | 1004 / 1335 | 0% | 0 | 0 / 0 |
| bladder | 62% | 112.29 | 13 / 21 | 5% | 0.45 | 26 / 504 |
| muscle | 60% | 105.53 | 483 / 803 | 0% | 0 | 0 / 0 |
| stomach | 37% | 96.45 | 132 / 359 | 3% | 0.06 | 10 / 286 |
| thymus | 34% | 66.60 | 219 / 653 | 0% | 0.00 | 1 / 605 |
| lung | 15% | 16.67 | 87 / 578 | 6% | 0.76 | 70 / 1155 |
| heart | 13% | 18.31 | 109 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 10% | 17.67 | 26 / 258 | 2% | 0.07 | 5 / 230 |
| uterus | 4% | 13.89 | 7 / 170 | 3% | 0.39 | 13 / 459 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.10 | 2 / 29 |
| pancreas | 1% | 1.23 | 4 / 328 | 3% | 0.18 | 5 / 178 |
| prostate | 4% | 8.61 | 9 / 245 | 0% | 0 | 0 / 502 |
| brain | 2% | 2.56 | 64 / 2642 | 1% | 0.01 | 7 / 705 |
| kidney | 2% | 5.07 | 2 / 89 | 1% | 0.03 | 7 / 901 |
| liver | 0% | 0 | 0 / 226 | 2% | 0.02 | 7 / 406 |
| peripheral blood | 1% | 0.46 | 5 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006508 | Biological process | proteolysis |
| GO_0043171 | Biological process | peptide catabolic process |
| GO_0005615 | Cellular component | extracellular space |
| GO_0016020 | Cellular component | membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0042277 | Molecular function | peptide binding |
| GO_0070006 | Molecular function | metalloaminopeptidase activity |
| GO_0008270 | Molecular function | zinc ion binding |
| Gene name | LVRN |
| Protein name | Aminopeptidase Q (AP-Q) (APQ) (EC 3.4.11.-) (CHL2 antigen) (Laeverin) |
| Synonyms | AQPEP |
| Description | FUNCTION: Metalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo-maternal interface. On synthetic substrates it shows a marked preference for Leu-4-methylcoumaryl-7-amide (Leu-MCA) over Met-MCA, Arg-LCA and Lys-LCA. Cleaves the N-terminal amino acid of several peptides such as angiotensin-3, kisspeptin-10 and endokinin C. . |
| Accessions | ENST00000504467.5 [Q6Q4G3-2] ENST00000514509.5 [Q6Q4G3-3] ENST00000512314.5 [Q6Q4G3-4] ENST00000503329.5 [Q6Q4G3-4] ENST00000357872.9 [Q6Q4G3-1] Q6Q4G3 |
