LRRC38 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of LRRC38 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of LRRC38 at tissue level.

III. Associated gene sets

GO_1903818Biological processpositive regulation of voltage-gated potassium channel activity
GO_0071805Biological processpotassium ion transmembrane transport
GO_0005886Cellular componentplasma membrane
GO_0008076Cellular componentvoltage-gated potassium channel complex
GO_0005249Molecular functionvoltage-gated potassium channel activity
GO_0099104Molecular functionpotassium channel activator activity
GO_0044325Molecular functiontransmembrane transporter binding

IV. Literature review

[source]
Gene nameLRRC38
Protein nameLeucine-rich repeat-containing protein 38 (BK channel auxiliary gamma subunit LRRC38)
Synonyms
DescriptionFUNCTION: Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium. .

AccessionsENST00000376085.4
Q5VT99