Insufficient scRNA-seq data for expression of LRFN1 at single-cell level.
Insufficient scRNA-seq data for expression of LRFN1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 99% | 1137.90 | 2607 / 2642 | 99% | 14.51 | 701 / 705 |
| breast | 83% | 174.14 | 383 / 459 | 90% | 7.62 | 1007 / 1118 |
| prostate | 69% | 136.56 | 170 / 245 | 99% | 9.68 | 499 / 502 |
| lung | 93% | 262.78 | 539 / 578 | 67% | 5.31 | 774 / 1155 |
| uterus | 86% | 279.84 | 146 / 170 | 62% | 6.76 | 286 / 459 |
| ovary | 43% | 90.17 | 77 / 180 | 95% | 15.69 | 408 / 430 |
| pancreas | 94% | 223.23 | 309 / 328 | 43% | 2.16 | 77 / 178 |
| skin | 53% | 93.08 | 950 / 1809 | 85% | 7.04 | 399 / 472 |
| esophagus | 32% | 50.33 | 461 / 1445 | 69% | 7.33 | 127 / 183 |
| eye | 0% | 0 | 0 / 0 | 100% | 14.25 | 80 / 80 |
| spleen | 100% | 573.47 | 241 / 241 | 0% | 0 | 0 / 0 |
| stomach | 58% | 97.48 | 207 / 359 | 42% | 3.76 | 119 / 286 |
| thymus | 71% | 130.86 | 463 / 653 | 27% | 1.71 | 166 / 605 |
| peripheral blood | 98% | 1871.31 | 913 / 929 | 0% | 0 | 0 / 0 |
| intestine | 70% | 141.15 | 673 / 966 | 25% | 1.51 | 131 / 527 |
| adrenal gland | 11% | 17.88 | 28 / 258 | 79% | 7.27 | 182 / 230 |
| adipose | 75% | 147.85 | 906 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 67% | 3.07 | 30 / 45 |
| bladder | 19% | 27.05 | 4 / 21 | 43% | 2.50 | 216 / 504 |
| lymph node | 0% | 0 | 0 / 0 | 59% | 2.07 | 17 / 29 |
| kidney | 13% | 20.78 | 12 / 89 | 33% | 1.13 | 295 / 901 |
| liver | 11% | 17.56 | 25 / 226 | 32% | 2.10 | 130 / 406 |
| blood vessel | 8% | 12.26 | 105 / 1335 | 0% | 0 | 0 / 0 |
| heart | 2% | 3.43 | 20 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0099151 | Biological process | regulation of postsynaptic density assembly |
| GO_0048787 | Cellular component | presynaptic active zone membrane |
| GO_0009986 | Cellular component | cell surface |
| GO_0098839 | Cellular component | postsynaptic density membrane |
| GO_0005886 | Cellular component | plasma membrane |
| Gene name | LRFN1 |
| Protein name | Leucine-rich repeat and fibronectin type III domain-containing protein 1 (Synaptic adhesion-like molecule 2) Alternative protein LRFN1 LRFN1 protein |
| Synonyms | KIAA1484 SALM2 |
| Description | FUNCTION: Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1 (By similarity). . |
| Accessions | Q96C50 Q9P244 ENST00000709040.1 ENST00000248668.5 L8E910 |