LIPT2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of LIPT2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of LIPT2 at tissue level.

III. Associated gene sets

GO_0009249Biological processprotein lipoylation
GO_2000376Biological processpositive regulation of oxygen metabolic process
GO_0019752Biological processcarboxylic acid metabolic process
GO_0005759Cellular componentmitochondrial matrix
GO_0005739Cellular componentmitochondrion
GO_0016874Molecular functionligase activity
GO_0033819Molecular functionlipoyl(octanoyl) transferase activity

IV. Literature review

[source]
Gene nameLIPT2
Protein nameOctanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial (Lipoate-protein ligase B) (Lipoyl/octanoyl transferase) (Lipoyltransferase 2) (EC 2.3.1.181) (Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase)
Lipoyl(octanoyl) transferase 2
Synonyms
DescriptionFUNCTION: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein (octanoyl-ACP) onto the lipoyl domains of lipoate-dependent enzymes such as the protein H of the glycine cleavage system (GCSH) . Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity). .

AccessionsH0YC96
A6NK58
ENST00000527115.1
H0YD50
ENST00000528085.1
ENST00000310109.5