Insufficient scRNA-seq data for expression of LIPI at single-cell level.
Insufficient scRNA-seq data for expression of LIPI at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 98% | 94.97 | 643 / 653 | 15% | 1.46 | 90 / 605 |
| uterus | 98% | 64.49 | 167 / 170 | 6% | 0.19 | 27 / 459 |
| ovary | 88% | 13.38 | 158 / 180 | 1% | 0.01 | 3 / 430 |
| esophagus | 81% | 14.94 | 1170 / 1445 | 7% | 0.11 | 13 / 183 |
| bladder | 81% | 14.71 | 17 / 21 | 2% | 0.04 | 11 / 504 |
| intestine | 78% | 34.79 | 750 / 966 | 1% | 0.02 | 4 / 527 |
| prostate | 59% | 4.99 | 145 / 245 | 0% | 0.00 | 1 / 502 |
| breast | 57% | 5.29 | 260 / 459 | 3% | 0.09 | 29 / 1118 |
| adipose | 51% | 4.62 | 618 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 46% | 3.41 | 610 / 1335 | 0% | 0 | 0 / 0 |
| brain | 43% | 4.99 | 1132 / 2642 | 2% | 0.03 | 15 / 705 |
| stomach | 38% | 7.49 | 138 / 359 | 2% | 0.04 | 5 / 286 |
| skin | 32% | 2.19 | 585 / 1809 | 1% | 0.01 | 4 / 472 |
| heart | 20% | 1.29 | 176 / 861 | 0% | 0 | 0 / 0 |
| lung | 17% | 1.12 | 100 / 578 | 2% | 0.06 | 27 / 1155 |
| pancreas | 18% | 1.13 | 60 / 328 | 1% | 0.02 | 1 / 178 |
| peripheral blood | 18% | 3.94 | 171 / 929 | 0% | 0 | 0 / 0 |
| spleen | 17% | 1.00 | 41 / 241 | 0% | 0 | 0 / 0 |
| adrenal gland | 14% | 0.68 | 36 / 258 | 0% | 0.38 | 1 / 230 |
| kidney | 9% | 0.49 | 8 / 89 | 3% | 0.17 | 26 / 901 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 2.68 | 2 / 29 |
| liver | 4% | 0.20 | 8 / 226 | 0% | 0 | 0 / 406 |
| muscle | 3% | 0.17 | 25 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006654 | Biological process | phosphatidic acid biosynthetic process |
| GO_0016042 | Biological process | lipid catabolic process |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0008201 | Molecular function | heparin binding |
| GO_0004620 | Molecular function | phospholipase activity |
| GO_0052689 | Molecular function | carboxylic ester hydrolase activity |
| Gene name | LIPI |
| Protein name | Lipase member I (LIPI) (EC 3.1.1.-) (Cancer/testis antigen 17) (CT17) (LPD lipase) (Membrane-associated phosphatidic acid-selective phospholipase A1-beta) (mPA-PLA1 beta) Lipase I Lipase member I |
| Synonyms | PRED5 LPDL |
| Description | FUNCTION: Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG). . |
| Accessions | ENST00000536861.6 [Q6XZB0-3] ENST00000536861 ENST00000614229.5 [Q6XZB0-5] A0A087WZG8 ENST00000679868.1 [Q6XZB0-8] A0A2Q2TCK2 H0Y3S0 ENST00000400211.3 Q6XZB0 ENST00000614229 ENST00000681601.1 [Q6XZB0-1] ENST00000680487.1 [Q6XZB0-7] ENST00000680801.1 [Q6XZB0-4] |