LIPI report

I. Expression across cell types

Insufficient scRNA-seq data for expression of LIPI at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of LIPI at tissue level.

III. Associated gene sets

GO_0006654Biological processphosphatidic acid biosynthetic process
GO_0016042Biological processlipid catabolic process
GO_0005615Cellular componentextracellular space
GO_0005886Cellular componentplasma membrane
GO_0008201Molecular functionheparin binding
GO_0004620Molecular functionphospholipase activity
GO_0052689Molecular functioncarboxylic ester hydrolase activity

IV. Literature review

[source]
Gene nameLIPI
Protein nameLipase member I (LIPI) (EC 3.1.1.-) (Cancer/testis antigen 17) (CT17) (LPD lipase) (Membrane-associated phosphatidic acid-selective phospholipase A1-beta) (mPA-PLA1 beta)
Lipase I
Lipase member I
SynonymsPRED5
LPDL
DescriptionFUNCTION: Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG). .

AccessionsENST00000536861.6 [Q6XZB0-3]
ENST00000536861
ENST00000614229.5 [Q6XZB0-5]
A0A087WZG8
ENST00000679868.1 [Q6XZB0-8]
A0A2Q2TCK2
H0Y3S0
ENST00000400211.3
Q6XZB0
ENST00000614229
ENST00000681601.1 [Q6XZB0-1]
ENST00000680487.1 [Q6XZB0-7]
ENST00000680801.1 [Q6XZB0-4]