Insufficient scRNA-seq data for expression of LGSN at single-cell level.
Insufficient scRNA-seq data for expression of LGSN at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 78% | 45.56 | 450 / 578 | 45% | 6.44 | 518 / 1155 |
| liver | 91% | 217.46 | 206 / 226 | 24% | 1.28 | 99 / 406 |
| kidney | 90% | 45.39 | 80 / 89 | 5% | 0.10 | 46 / 901 |
| stomach | 77% | 48.15 | 275 / 359 | 13% | 0.78 | 36 / 286 |
| spleen | 87% | 19.48 | 210 / 241 | 0% | 0 | 0 / 0 |
| prostate | 69% | 39.77 | 169 / 245 | 4% | 0.11 | 19 / 502 |
| pancreas | 60% | 19.60 | 196 / 328 | 4% | 0.40 | 7 / 178 |
| intestine | 40% | 14.41 | 384 / 966 | 9% | 0.40 | 46 / 527 |
| peripheral blood | 45% | 13.51 | 417 / 929 | 0% | 0 | 0 / 0 |
| bladder | 29% | 5.33 | 6 / 21 | 13% | 0.76 | 65 / 504 |
| ovary | 8% | 1.03 | 14 / 180 | 30% | 0.92 | 129 / 430 |
| adrenal gland | 24% | 2.58 | 61 / 258 | 2% | 0.11 | 5 / 230 |
| brain | 25% | 7.03 | 670 / 2642 | 0% | 0.01 | 1 / 705 |
| esophagus | 2% | 0.21 | 34 / 1445 | 13% | 0.81 | 24 / 183 |
| skin | 5% | 0.61 | 86 / 1809 | 9% | 0.25 | 42 / 472 |
| muscle | 12% | 1.29 | 98 / 803 | 0% | 0 | 0 / 0 |
| uterus | 4% | 0.66 | 7 / 170 | 8% | 0.27 | 35 / 459 |
| thymus | 9% | 0.88 | 60 / 653 | 0% | 0.02 | 2 / 605 |
| breast | 2% | 0.30 | 9 / 459 | 3% | 0.08 | 29 / 1118 |
| adipose | 4% | 0.42 | 52 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.04 | 1 / 29 |
| heart | 3% | 0.27 | 28 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 2% | 0.18 | 27 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006542 | Biological process | glutamine biosynthetic process |
| GO_0019740 | Biological process | nitrogen utilization |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0004356 | Molecular function | glutamine synthetase activity |
| Gene name | LGSN |
| Protein name | Lengsin (Glutamate-ammonia ligase domain-containing protein 1) (Lens glutamine synthase-like) Lengsin, lens protein with glutamine synthetase domain |
| Synonyms | LGS GLULD1 |
| Description | FUNCTION: May act as a component of the cytoskeleton or as a chaperone for the reorganization of intermediate filament proteins during terminal differentiation in the lens. Does not seem to have enzymatic activity (By similarity). . |
| Accessions | A0A0A0MTD2 ENST00000370658.9 [Q5TDP6-2] Q5TDP6 ENST00000485906.6 ENST00000370657.9 [Q5TDP6-1] ENST00000622415.1 [Q5TDP6-3] |