LEAP2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
enterocyte	6 studies	22% ± 3%	Explore
hepatocyte	4 studies	71% ± 14%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
liver	3 studies	32% ± 6%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	8249.80	226 / 226	99%	191.68	403 / 406
brain	95%	162.25	2506 / 2642	97%	3.51	686 / 705
prostate	100%	372.98	245 / 245	90%	2.85	451 / 502
pancreas	99%	147.13	326 / 328	89%	3.78	158 / 178
intestine	100%	271.18	965 / 966	87%	3.15	461 / 527
kidney	100%	323.08	89 / 89	87%	5.83	781 / 901
stomach	99%	217.00	355 / 359	83%	2.42	238 / 286
uterus	100%	185.24	170 / 170	82%	2.66	375 / 459
bladder	100%	510.10	21 / 21	80%	9.21	403 / 504
breast	100%	167.87	458 / 459	76%	2.44	852 / 1118
thymus	100%	309.23	653 / 653	75%	1.87	451 / 605
esophagus	99%	163.46	1435 / 1445	72%	2.13	131 / 183
ovary	100%	163.47	180 / 180	60%	1.34	257 / 430
lung	99%	166.77	573 / 578	60%	1.42	695 / 1155
adrenal gland	97%	127.01	250 / 258	61%	1.18	141 / 230
skin	97%	154.73	1753 / 1809	42%	0.83	198 / 472
spleen	100%	332.80	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	1.37	1 / 1
adipose	98%	137.01	1175 / 1204	0%	0	0 / 0
muscle	97%	125.72	777 / 803	0%	0	0 / 0
blood vessel	96%	95.43	1283 / 1335	0%	0	0 / 0
heart	96%	112.80	823 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	93%	3.18	27 / 29
peripheral blood	84%	101.44	777 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	67%	1.86	30 / 45
eye	0%	0	0 / 0	28%	0.50	22 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0