I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| pericyte | 11 studies | 47% ± 17% | |
| fibroblast | 3 studies | 30% ± 8% | |
| endothelial cell | 3 studies | 28% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| pericyte | 11 studies | 47% ± 17% | |
| fibroblast | 3 studies | 30% ± 8% | |
| endothelial cell | 3 studies | 28% ± 9% |
Insufficient scRNA-seq data for expression of LAMC3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 96% | 1621.93 | 234 / 245 | 82% | 5.37 | 411 / 502 |
| lung | 100% | 7796.34 | 577 / 578 | 72% | 5.63 | 826 / 1155 |
| adrenal gland | 100% | 4594.90 | 258 / 258 | 66% | 16.09 | 151 / 230 |
| kidney | 98% | 3306.83 | 87 / 89 | 64% | 7.44 | 573 / 901 |
| bladder | 100% | 5354.19 | 21 / 21 | 55% | 3.60 | 277 / 504 |
| pancreas | 80% | 682.84 | 263 / 328 | 69% | 4.40 | 123 / 178 |
| liver | 81% | 898.37 | 183 / 226 | 64% | 5.97 | 259 / 406 |
| brain | 55% | 338.28 | 1456 / 2642 | 86% | 6.63 | 607 / 705 |
| skin | 72% | 1979.87 | 1309 / 1809 | 61% | 6.71 | 287 / 472 |
| uterus | 49% | 1403.55 | 83 / 170 | 72% | 7.16 | 330 / 459 |
| ovary | 53% | 493.82 | 96 / 180 | 62% | 5.16 | 267 / 430 |
| spleen | 100% | 4354.51 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 2.06 | 1 / 1 |
| eye | 0% | 0 | 0 / 0 | 99% | 18.29 | 79 / 80 |
| esophagus | 24% | 165.61 | 349 / 1445 | 64% | 4.92 | 118 / 183 |
| breast | 50% | 570.64 | 228 / 459 | 24% | 1.22 | 268 / 1118 |
| thymus | 48% | 398.75 | 311 / 653 | 10% | 0.55 | 62 / 605 |
| intestine | 26% | 224.04 | 250 / 966 | 27% | 1.39 | 144 / 527 |
| blood vessel | 52% | 462.22 | 693 / 1335 | 0% | 0 | 0 / 0 |
| stomach | 6% | 45.47 | 23 / 359 | 33% | 1.66 | 95 / 286 |
| adipose | 39% | 311.90 | 471 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 31% | 1.47 | 9 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 22% | 2.10 | 10 / 45 |
| heart | 15% | 86.50 | 127 / 861 | 0% | 0 | 0 / 0 |
| muscle | 1% | 8.71 | 11 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0.46 | 1 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007601 | Biological process | visual perception |
| GO_0014002 | Biological process | astrocyte development |
| GO_0000902 | Biological process | cell morphogenesis |
| GO_0007155 | Biological process | cell adhesion |
| GO_0060041 | Biological process | retina development in camera-type eye |
| GO_0005604 | Cellular component | basement membrane |
| GO_0005576 | Cellular component | extracellular region |
| GO_0031012 | Cellular component | extracellular matrix |
| GO_0016020 | Cellular component | membrane |
| GO_0005198 | Molecular function | structural molecule activity |
| Gene name | LAMC3 |
| Protein name | Laminin subunit gamma-3 (Laminin-12 subunit gamma) (Laminin-14 subunit gamma) (Laminin-15 subunit gamma) Laminin subunit gamma 3 |
| Synonyms | |
| Description | FUNCTION: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
| Accessions | ENST00000355452.5 ENST00000679272.1 H7BY04 ENST00000678758.1 A0A7I2YQP4 A0A7I2V3S4 ENST00000361069.9 Q9Y6N6 |
